070328: Vancomycin, Serum, Trough | Labcorp

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4. 070328: Vancomycin, Serum, Trough

Vancomycin, Serum, Trough Test Number 070328Test number copied CPT 80202 Synonyms

• Vancocin®

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• Test Details
• Specimen Requirements
• LOINC®

Test Details

Methodology

Immunoassay

Result Turnaround Time

Within 1 day

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

• Sample Report

Use

Monitor therapeutic drug level

Special Instructions

Peak levels should be ordered using Test No. 070327. Trough levels should be ordered using Test No. 070328. Please label tubes appropriately as “peak” and “trough.”

Specimen Requirements

Specimen

Serum or plasma

Volume

1 mL

Minimum Volume

0.3 mL

Container

Red-top tube, lavender-top (K2- or K3- EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.

Collection Instructions

Transfer separated serum or plasma to a plastic transport tube. Trough concentrations should be monitored. The trough sample is drawn immediately prior to the next dose.

Stability Requirements

Temperature	Period
Room temperature	3 days
Refrigerated	14 days
Frozen	14 days
Freeze/thaw cycles	Stable x3

Storage Instructions

Refrigerate

Causes for Rejection

Gel-barrier tube; hemolysis; lipemia; gross bacterial contamination

References

AMA Division of Drugs and Toxicology, Drug Evaluations Subscription, Chicago, IL: American Medical Association, Spring 1990.Brunton L, Lazo J, Parker K. Goodman & Gillman's The Pharmacological Basis of Therapeutics. 11th ed. New York, NY: McGraw-Hill, 2006.Burtis CA, Ashwood CR, Bruns DE. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. St Louis, MO: Elsevier Saunders, 2006.Dart RC, Caravati EM, McGuigan MA, et al. Medical Toxicology. Philadelphia, PA: Lippincott Williams & Wilkins, 2006.Mosby's Drug Consult. 17th ed. St Louis, MO: Elsevier Saunders, 2007.Rybak M, Lomaestro B, Rotschafer JC, et al. Therapeutic Monitoring of Vancomycin in Adult Patients: A consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists. Am J Health Syst Pharm. 2009 Jan 1;(66)(1)82-98.19106348

LOINC® Map

Order Code	Order Code Name	Order Loinc	Result Code	Result Code Name	UofM	Result LOINC
070328	Vancomycin Trough, Serum	4092-3	070338	Vancomycin Trough, Serum	ug/mL	4092-3
Order Code	070328
Order Code Name	Vancomycin Trough, Serum
Order Loinc	4092-3
Result Code	070338
Result Code Name	Vancomycin Trough, Serum
UofM	ug/mL
Result LOINC	4092-3