2022 Michigan State Spartans Schedule - College Football
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| Date | OPP | Result | Record |
|---|---|---|---|
| Aug 29, 2025 | vs  | W 23-6 | 1-0 |
| Sep 6, 2025 | vs  | W 42-40 / 2OT | 2-0 |
| Sep 13, 2025 | vs  | W 41-24 | 3-0 |
| Sep 20, 2025 | @  | L 45-31 | 3-1 |
| Oct 4, 2025 | @  | L 38-27 | 3-2 |
| Oct 11, 2025 | vs  | L 38-13 | 3-3 |
| Oct 18, 2025 | @  | L 38-13 | 3-4 |
| Oct 25, 2025 | vs  | L 31-20 | 3-5 |
| Nov 1, 2025 | @  | L 23-20 / OT | 3-6 |
| Nov 15, 2025 | vs  | L 28-10 | 3-7 |
| Nov 22, 2025 | @  | L 20-17 | 3-8 |
| Nov 29, 2025 | vs  | W 38-28 | 4-8 |
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