ABSTRACT 501: CORONARY PERFUSION PRESSURE IN THE ...

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May 2014 - Volume 15 - Issue 4_suppl
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Abstracts of the 7th World Congress on Pediatric Critical Care

Ahmed, M.1; Yuerek, M.1; Bhutta, A.T.1

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1Pediatric Critical Care Medicine, UAMS - Arkansas Children’s Hospital, Little Rock, USA

Pediatric Critical Care Medicine 15(4_suppl):p 114, May 2014. | DOI: 10.1097/01.pcc.0000449227.67207.bd
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Background and aims: Previous studies have investigated the correlation of coronary perfusion pressure and return of circulation in humans and animals. Currently, there is no data available in pediatric population. With regard to the physiologic changes a growing child is going through, the physiologic coronary perfusion pressure changes with age. Studies in adult patients report a normal coronary perfusion pressure of 60–80 mmHg. A recent retrospective study in adults reported a coronary perfusion pressure of 45 mmHg in survivors of cardiogenic shock.

Aims: Our aim is to investigate the coronary perfusion pressure in pediatric patients post palliative procedures for congenital heart disease. Currently, we have prelimenary results available for children aged 2–8 years, who underwent Fontan procedure. We hope to define normal values for coronary perfusion pressure in this specialized patient population.

Methods: In our institution Fontan patients are monitored with atrial line, arterial line and right internal jugularis line in the immediate postoperative phase. Continuous hemodynamic data was availabe for 32 patients, who underwent Fontan procedure from July 2010 - October 2013. IRB approval was granted by our institution. We calculated the coronary perfusion pressure by substracting the atrial pressure from the diastolic blood pressure every 15 seconds. Averages over 5 minutes were calculated.

Results: The average coronary perfusion pressure 44.9 mm Hg with a standard deviation of +/- 6.8 mmHg in ages 2–4 years old.

Conclusions: In this retrospective analysis coronary perfusion pressures in patients status post Fontan procedure averaged 44.9 mm Hg with a standard deviation of 6.8 mm Hg. Further studies are required to determine correlation with outcome.

©2014The Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care SocietiesView full article text

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ABSTRACT 501: CORONARY PERFUSION PRESSURE IN THE INITIAL 24 HOURS POST FONTAN PROCEDURE Pediatric Critical Care Medicine15(4_suppl):114, May 2014.
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