Acetaminophen 325mg - Arthritis Foundation

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Last Updated: 12/23/2024

Acetaminophen 325 mg

Drug Name(s): Anacin (aspirin-free), Excedrin, Tylenol Regular Strength, generic

Class: Analgesics

Type: Non-Opioid

Used to relieve arthritis pain, and muscular pain.

Dosage

Form(s): capsule, oral liquid, tablet, orally disintegrating tablet Two 325-mg pills every 4 to 6 hours, no more than 10 tablets (3,250 mg) a day.

Special Instructions

Take with or without food. Allow disintegrating tablet to dissolve in your mouth before swallowing. Shake the suspension well before each use to mix the medication evenly. Always use the measuring cup or syringe provided by the manufacturer.

Potential Side Effects

Acetaminophen is generally safe when taken as directed.

Be Aware

Do not use with any other products containing acetaminophen. Too much acetaminophen can cause serious liver damage or death. Limit the amount of acetaminophen you take to 4000 mg/day unless otherwise directed by your doctor. Drinking alcohol increases your risk of liver damage. Tell your doctor if you have a history of liver disease or alcohol or drug abuse, or if you have three or more alcoholic drinks daily. Also tell your doctor if you take the blood-thinning drug warfarin (Coumadin). Acetaminophen prolongs the time that drug is active in your body, increasing bleeding risk. Your doctor may need to adjust your dosage. Rarely, acetaminophen may cause serious skin reactions, including Stevens-Johnson syndrome, which can be deadly. Stop taking acetaminophen and call your doctor if you develop a skin rash.

The Arthritis Foundation’s Drug Guide is meant for education — not self-medicating. The Arthritis Foundation does not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.

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