Top Most 15+ Active Metabolites 6-thioguanine Nucleotides
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1.Importance Of 6-Thioguanine Nucleotide Metabolite Monitoring In ...
1 mai 2019
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2.Measurements Of 6-thioguanine Nucleotide Levels With TPMT And ...
5 déc. 2017 · This study aimed to determine the relationship between thiopurine metabolite levels and therapeutic response, and to investigate the association ... Abstract · Introduction · Materials and methods · Results
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3.Association Of 6-Thioguanine Nucleotide Levels And Inflammatory ...
Background & Aims: 6-Thioguanine nucleotide (6-TGN) levels have been proposed to correlate with inflammatory bowel disease (IBD) activity among patients ... Materials and Methods · Results · Discussion · References
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4.Thioguanine Nucleotides And Thiopurine Methyltransferase In ...
1 juin 2009 · Main Outcome Measures Blood levels of 6-thioguanine nucleotide, ... metabolites rather than to active metabolites has been described.
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5.Tioguanine - An Overview | ScienceDirect Topics
The 6-thioguanines are the active metabolites that interfere with purine nucleotide synthesis within the cell cycle, and they thereby impair proliferation ...
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6.Measurement Of Thiopurine Methyltransferase Activity And ... - Gut
Median 6-thioguanine nucleotide concentrations in 56 patients with active ... metabolite 6-MMP and towards production of the “active” metabolite 6-TGN.5.
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7.Systematic Review And Meta-Analysis Of 6-Thioguanine Nucleotide ...
30 juin 2017 · Mean 6-thioguanine nucleotide levels were higher among patients in clinical ... Their pharmacologically active metabolites are 6-thioguanine ...
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8.[PDF] Thiopurines' Metabolites And Drug Toxicity: A Meta-Analysis - MDPI
13 juil. 2020 · Levels of 6-thioguanine nucleotides (6-TGN) were higher in patients ... of the active metabolite 6-TGN, leading to the formation of ...
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9.Therapeutic Drug Monitoring Of Thiopurines: Effect Of Reduced 6 ...
16 mars 2022 · The metabolism of thiopurines is characterized by formation of the active 6-thioguanine nucleotides (6-TGN) metabolites and toxic ...
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10.Analytical Pitfalls Of Therapeutic Drug Monitoring Of Thiopu...
Bold lines represent the purine salvage pathway in which the pharmacologically active metabolites [6-thioguanine nucleotides (6-TGN)] are formed, ...
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11.[PDF] Importance Of 6-thioguanine Nucleotide Metabolite Monitoring In ...
The active metabolite of azathioprine, 6-thioguanine nucleotide (6-TGN) is the main component responsible for the immunosuppressive effect in treatment of ...
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12.[PDF] Role Of Thiopurine Metabolite Testing And Thiopurine ... - NASPGHAN
and thiopurine (TP) metabolites, 6-thioguanine nucleotides (6-TGN) and ... active CD (5) and in maintaining remission afterward (6). In active.
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13.[PDF] How Should Thiopurine Treatment Be Monitored? Methodological ...
Lennard, L. Assay of 6-thioinosinic acid and 6-thioguanine nucleotides, active metabolites of 6- mercaptopurine, in human red blood cells, J Chromatogr 1987 ...
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14.Thiopurine Metabolite Levels In Patients With Atopic Dermatitis And/or ...
13 août 2017 · It is converted in the liver into active metabolites, including 6-thioguanine nucleotide (6-TGN) and methylated 6-methylmercaptopurine.
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15.Pretreatment Testing And Approach To Therapeutic Drug Monitoring For ...
The immunosuppressive properties of AZA/6-MP are mediated by the intracellular metabolism of 6-MP into its active metabolites, 6-thioguanine nucleotides ...
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