How Much CBD Should I Take The First Time? - Healthline

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HealthlineSubscribeHow Much CBD Should I Take the First Time?

Medically reviewed by Alex Nguyen, PharmD, RPh, CPh — Written by Adrienne Santos-Longhurst — Updated on April 9, 2025

Factors
Onset
Re-dosing
Duration
First-time tips
Takeaway

Wondering how much CBD to take for the first time? This guide breaks down the factors that affect your ideal dose, helping you find the right amount to start with for maximum benefits and minimal side effects.

Figuring out how much CBD, or cannabidiol, to take is more complex than it sounds. While cannabis has been around for forever, CBD products are relatively new. As a result, there aren’t any evidence-based dosing guidelines yet.

Most experts agree that if it’s your first time using CBD, starting with the lowest dose and gradually working your way up is the best way to go.

Here’s a look at what you should know before trying CBD for the first time.

It depends on a few things

For starters, your body weight and individual body chemistry affect how you tolerate CBD.

Here are some other factors that play into how much CBD you should use.

How you take it

There are a few different ways to use CBD. The form matters when it comes to how much you should take, how it’s absorbed by your body, and how quickly it takes effect.

The different forms include:

oils and tinctures
gummies
capsules
creams and lotions

Doses vary among forms. For instance, a standard dose in CBD gummies is around 5 milligrams (mg) per gummy, while tinctures and oils contain about 1 mg per drop.

Capsules and gummies may take longer to kick in than an oil or tincture.

What you’re using it for

People use CBD to treat everything from nausea to arthritis pain. What you’re using it for matters when deciding how much you should take.

For instance, the Arthritis Foundation recommends starting slow with just a few milligrams of a sublingual form of CBD twice a day and increasing the dose by the same amount after a week if you don’t get enough pain relief.

That recommendation may not be the same if you’re using CBD for another condition.

Other medications

If you’re on any other medications, it’s important to know exactly how much, if any, CBD you should take.

CBD is usually well tolerated, but there’s still limited data on drug interactions. CBD may change the way a drug is metabolized. If you’re taking any other medications, speak to your doctor before using CBD.

When should it start working?

It depends on how you take it.

Gummies go through your digestive tract before they’re absorbed. By the time this happens, the actual amount of CBD that ends up in your system could be fairly low.

Another form, such as a CBD oil that you take sublingually, gets absorbed directly into your bloodstream, meaning it kicks in faster.

CBD onset time

Here’s a look at how long it generally takes to feel the effects of different forms of CBD:

Gummies: up to 2 hours
Oils or tinctures: 15 to 45 minutes
Topicals: 45 to 60 minutes

Should I take more?

Not so fast!

Re-dosing is one of the most common reasons why people end up taking too much of anything. If you take more too soon, you could end up with unwanted effects.

Again, CBD is generally well tolerated, even at high doses, but that doesn’t mean it’s harmless.

Taking too much could result in:

diarrhea
fatigue
appetite changes

Start low and slow, and make sure you give the CBD ample time to work before taking more. The general rule of thumb is to take a low dose for about a week before increasing it.

How long will it last?

In general, the effects of CBD last from 2 to 6 hours, depending on how you use it, how much you use, and your tolerance.

To better understand how your body reacts to it, take some general notes when using CBD, including:

the amount you took and how you took it
when you started feeling the effects
how strong the effects were
how long the effects lasted

This information can help you decide how much to take next time, as well as when to take it.

Newbie tips

Ready to join the world of CBD? These tips will help to ensure your experience is as comfortable, safe, and effective as possible:

Shop smart: CBD products are largely unregulated in the United States. Mislabeling and poor quality control, including significant discrepancies in strength and undeclared THC, or tetrahydrocannabinol, are an issue. Only shop from trusted, licensed companies. The team at Healthline vets and tests CBD products.
Ask a professional: A healthcare professional who knows your medical history is the best person to go to for advice about how much CBD you take. As knowledgeable as sales staff may be when it comes to CBD products, they aren’t healthcare professionals. Your best bet is to consult both.
Use it before bedtime: Drowsiness is one of the most common side effects of CBD. Unless your healthcare professional advises otherwise, using CBD at bedtime — or when you have time to chill if you need to — is a good idea, at least until you know how your body responds to it.
Avoid vaping: Vaping has been linked to serious lung infections and even death, though it’s not exactly clear how or why. While the Centers for Disease Control and Prevention (CDC) are investigating the risks of vaping, most government health agencies recommend avoiding vaping until we know more.

The takeaway

CBD is typically safe and well tolerated, but it’s not a one-size-fits-all solution. There are several factors that play into how much and how often you should use it.

Until experts come up with clinical guidelines, your best bet is to talk to your healthcare provider, especially if you’re using CBD to manage a specific condition or regularly take a medication for a specific condition.

Is CBD legal? The 2018 Farm Bill removed hemp from the legal definition of marijuana in the Controlled Substances Act. This made some hemp-derived CBD products with less than 0.3% THC legal at the federal level. However, CBD products containing more than 0.3% THC still fall under the legal definition of marijuana, making them illegal at the federal level. Some states have legalized CBD, so be sure to check state laws, especially when traveling. Also, keep in mind that the FDA has not approved nonprescription CBD products, and some products may be inaccurately labeled.

How we reviewed this article:

SourcesHistoryHealthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

CBD for arthritis pain: what you should know (2024).https://www.arthritis.org/health-wellness/healthy-living/managing-pain/pain-relief-solutions/cbd-for-arthritis-pain
Health effects of vaping. (2025).https://www.cdc.gov/tobacco/e-cigarettes/health-effects.html
Ho JJY, et al. (2024). Evaluation of potential drug-drug interactions with medical cannabis.https://pmc.ncbi.nlm.nih.gov/articles/PMC11079547/

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Medically reviewed by Alex Nguyen, PharmD, RPh, CPh — Written by Adrienne Santos-Longhurst — Updated on April 9, 2025

How Much CBD Should I Take The First Time? - Healthline

It depends on a few things

How you take it

What you’re using it for

Other medications

When should it start working?

CBD onset time

Should I take more?

How long will it last?

Newbie tips

The takeaway

How we reviewed this article:

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