How To (ab)use A COVID-19 Antigen Rapid Test With Soft Drinks?

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Abstract

With reasonably good specificity and sensitivity, the speed and convenience of COVID-19 antigen tests have led to self-testing in schools, offices, and universities in the European Union (EU). Although self-testing can be beneficial and increase the accessibility to testing, there are potential ways to confound a positive COVID-19 lateral flow test. We observed that all soft drinks, energy drinks, alcoholic beverages (vodka, whiskey, and brandy), commercially bottled mineral water, and carbonated mineral water caused the appearance of a red test line. However, when equal volumes of the buffer and the respective beverages are mixed, there are no false-positive test lines. Deceitful methods may easily lead to misuse of COVID-19 antigen rapid tests and lead to false-positive results; however, this does not prove that these tests are unreliable when performed correctly.

Keywords: RDTs; SARS-CoV-2; antigen test; false-positive.

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Figures

Figure 1:

Figure 1

Soft drinks, alcoholic beverages, energy…

Figure 1

Soft drinks, alcoholic beverages, energy drinks, and water directly used as a sample.

Figure 1 Soft drinks, alcoholic beverages, energy drinks, and water directly used as a sample.
Figure 2:

Figure 2

Soft drinks, alcoholic beverages, energy…

Figure 2

Soft drinks, alcoholic beverages, energy drinks, and water equally mixed with the recommended…

Figure 2 Soft drinks, alcoholic beverages, energy drinks, and water equally mixed with the recommended buffer volume
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Comment in

  • The fake positive results of COVID-19 rapid antigen tests with the use of beverages vary between brands of test kits. Castro-Rodriguez B, Morales-Jadan D, Viteri-Davila C, Rodriguez AS, Ortiz-Prado E, Garcia-Bereguiain MA. Castro-Rodriguez B, et al. Int J Infect Dis. 2023 Nov;136:149-150. doi: 10.1016/j.ijid.2023.09.008. Epub 2023 Sep 22. Int J Infect Dis. 2023. PMID: 37742715 No abstract available.

References

    1. Velavan TP, Meyer CG. COVID-19: A PCR-defined pandemic. Int J Infect Dis. 2021:278–279. Feb; 103. - PMC - PubMed

MeSH terms

  • Antigens, Viral Actions
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  • COVID-19 Testing Actions
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  • COVID-19* Actions
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  • Carbonated Beverages Actions
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  • Humans Actions
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  • Antigens, Viral Actions
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