Immune-Mediated Hemolytic Anemia | Today's Veterinary Practice

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1. Immune-mediated hemolytic anemia (IMHA) is a good example of which type of immune-mediated reaction?

a. Type I (allergic)

b. Type II (cytotoxic)

c. Type III (immune complex)

d. Type IV (delayed)

2. Which of the following clinical features does not strongly suggest the presence of intravascular hemolysis?

a. Hemoglobinemia

b. Hemoglobinuria

c. Jaundice

d. Ghost cells

3. Which organ is most likely to be damaged by the presence of intravascular hemolysis?

a. Brain

b. Heart

c. Liver

d. Kidney

4. Which of the following infectious diseases has been strongly associated with secondary IMHA in dogs?

a. Brucellosis

b. Leptospirosis

c. Babesiosis

d. Bartonellosis

5. Evans syndrome should be suspected in IMHA patients that have what abnormality on routine complete blood count evaluation?

a. Marked thrombocytopenia

b. Marked neutrophilia

c. Pancytopenia

d. Schistocytosis

6. Which red blood count abnormality strongly supports a diagnosis of IMHA in dogs?

a. Heinz bodies

b. Eccentrocytes

c. Schistocytes

d. Spherocytes

7. Which of the following immunosuppressive agents has no known marrow suppressive effects?

a. Azathioprine

b. Mycophenolate mofetil

c. Leflunomide

d. Cyclosporine

8. Which of the following immunosuppressive agents is considered to be highly dangerous in cats?

a. Prednisolone

b. Cyclosporine

c. Mycophenolate mofetil

d. Azathioprine

9. Which is the preferred blood product for transfusing dogs with IMHA?

a. Fresh frozen plasma

b. Packed red blood cells that are fresh or have been stored for fewer than 10 days

c. Whole blood that is fresh or has been stored for fewer than 10 days

d. Whole blood that has been stored for more than 10 days

10. Which of the following anticoagulants used to prevent pulmonary thromboembolism can be given orally?

a. Unfractionated heparin

b. Dalteparin

c. Enoxaparin

d. Rivaroxaban