Info: Seachem Prime® Dosing Instructions - Knowledge Base

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Use 1 capful (5 mL) for each 200 L (50 US gallons) of new water. For smaller volumes, please note each cap thread is approximately 1 mL. May be added to aquarium directly, but better if added to new water first. If adding directly to aquarium, base dose on aquarium volume. Sulfur odor is normal. For exceptionally high chloramine concentrations, a double dose may be used safely. To detoxify nitrite in an emergency, up to 5 times normal dose may be used. If temperature is > 30 °C (86 °F) and chlorine or ammonia levels are low, use a half dose.

Prime® Dosing Tables

Standard Dose

Use this table when doing a water change or detoxifying low levels of ammonia (around 1 ppm)

Water Volume 1 qt / 1 L 1 gal / 4 L 10 gal / 40 L 50 gal / 200 L
Prime® Dose (mL) 0.025 mL 0.1 mL 1 mL 5 mL
Prime® Dose (caps) 1/200 capful 1/50 capful 1/5 capful 1 capful
Prime® Dose (drops) 0.5 drops 2 drops 20 drops 100 drops

Double Dose

Use this table only when there are elevated levels of ammonia (around 2 ppm), nitrite, chlorine, or chloramine

Water Volume 1 qt / 1 L 1 gal / 4 L 10 gal / 40 L 50 gal / 200 L
Prime® Dose (mL) 0.05 mL 0.2 mL 2 mL 10 mL
Prime® Dose (caps) 1/100 capful 1/25 capful 2/5 capful 2 capfuls
Prime® Dose (drops) 1 drops 4 drops 40 drops 200 drops

Triple Dose

Use this table only when there are very elevated levels of ammonia (around 3 ppm) or nitrite

It is unheard of to have chlorine or chloramine concentrations at this level in tap water

Water Volume 1 qt / 1 L 1 gal / 4 L 10 gal / 40 L 50 gal / 200 L
Prime® Dose (mL) 0.075 mL 0.3 mL 3 mL 15 mL
Prime® Dose (caps) 3/200 capful 3/50 capful 3/5 capful 3 capfuls
Prime® Dose (drops) 1.5 drops 6 drops 60 drops 300 drops

Quadruple Dose

Use this table only when there are extremely elevated levels of ammonia (around 4 ppm) or nitrite

It is unheard of to have chlorine or chloramine concentrations at this level in tap water

Water Volume 1 qt / 1 L 1 gal / 4 L 10 gal / 40 L 50 gal / 200 L
Prime® Dose (mL) 0.1 mL 0.4 mL 4 mL 20 mL
Prime® Dose (caps) 1/50 capful 2/25 capful 4/5 capful 4 capfuls
Prime® Dose (drops) 2 drops 8 drops 80 drops 400 drops

MAXIMUM DOSE

Use this table only when there are extremely elevated levels of ammonia (around 5 ppm) or nitrite

It is unheard of to have chlorine or chloramine concentrations at this level in tap water

Water Volume 1 qt / 1 L 1 gal / 4 L 10 gal / 40 L 50 gal / 200 L
Prime® Dose (mL) 0.125 mL 0.5 mL 5 mL 25 mL
Prime® Dose (caps) 1/25 capful 4/25 capful 1 capful 5 capfuls
Prime® Dose (drops) 2.5 drops 10 drops 100 drops 500 drops

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