Introduction To The Respiratory System - SEER Training

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When the respiratory system is mentioned, people generally think of breathing, but breathing is only one of the activities of the respiratory system. The body cells need a continuous supply of oxygen for the metabolic processes that are necessary to maintain life. The respiratory system works with the circulatory system to provide this oxygen and to remove the waste products of metabolism. It also helps to regulate pH of the blood.

Respiration is the sequence of events that results in the exchange of oxygen and carbon dioxide between the atmosphere and the body cells. Every 3 to 5 seconds, nerve impulses stimulate the breathing process, or ventilation, which moves air through a series of passages into and out of the lungs. After this, there is an exchange of gases between the lungs and the blood. This is called external respiration. The blood transports the gases to and from the tissue cells. The exchange of gases between the blood and tissue cells is internal respiration. Finally, the cells utilize the oxygen for their specific activities: this is called cellular metabolism, or cellular respiration. Together, these activities constitute respiration.

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Suggested Citation

SEER Training Modules: Introduction to the Respiratory System. U.S. National Institutes of Health, National Cancer Institute. Cited 06 February 2026. Available from: https://training.seer.cancer.gov.

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