IPECAC - Uses, Side Effects, And More - WebMD

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Ipecac for the home treatment of poisonings. Pharmacist's Letter/Prescriber's Letter 2003;19(12):191201.

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Wax, P. M., Cobaugh, D. J., and Lawrence, R. A. Should home ipecac-induced emesis be routinely recommended in the management of toxic berry ingestions? Vet.Hum.Toxicol. 1999;41(6):394-397.

Scharman, E. J., Hutzler, J. M., Rosencrance, J. G., and Tracy, T. S. Single dose pharmacokinetics of syrup of ipecac. Ther.Drug Monit. 2000;22(5):566-573.

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Bond, G. R. Home syrup of ipecac use does not reduce emergency department use or improve outcome. Pediatrics 2003;112(5):1061-1064.

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Silber, T. J. Ipecac syrup abuse, morbidity, and mortality: isn't it time to repeal its over-the-counter status? J Adolesc.Health 2005;37(3):256-260.

Rashid, N. Medically unexplained myopathy due to ipecac abuse. Psychosomatics 2006;47(2):167-169.

Kornberg, A. E. and Dolgin, J. Pediatric ingestions: charcoal alone versus ipecac and charcoal. Ann.Emerg.Med 1991;20(6):648-651.

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Lee, M. R. Ipecacuanha: the South American vomiting root. J R.Coll.Physicians Edinb. 2008;38(4):355-360.

Stiell, I. G. Activated charcoal alone versus activated charcoal & ipecac. Ann.Emerg.Med. 1990;19(10):1202-1204.

Merigian, K. S., Woodard, M., Hedges, J. R., Roberts, J. R., Stuebing, R., and Rashkin, M. C. Prospective evaluation of gastric emptying in the self-poisoned patient. Am J Emerg.Med 1990;8(6):479-483.

Albertson, T. E., Derlet, R. W., Foulke, G. E., Minguillon, M. C., and Tharratt, S. R. Superiority of activated charcoal alone compared with ipecac and activated charcoal in the treatment of acute toxic ingestions. Ann.Emerg.Med 1989;18(1):56-59.

Tandberg, D. and Murphy, L. C. The knee-chest position does not improve the efficacy of ipecac-induced emesis. Am.J.Emerg.Med. 1989;7(3):267-270.

Day, L., Kelly, C., Reed, G., Andersen, J. M., and Keljo, J. M. Fatal cardiomyopathy: suspected child abuse by chronic ipecac administration. Vet.Hum.Toxicol. 1989;31(3):255-257.

McNamara, R. M., Aaron, C. K., Gemborys, M., and Davidheiser, S. Efficacy of charcoal cathartic versus ipecac in reducing serum acetaminophen in a simulated overdose. Ann.Emerg.Med 1989;18(9):934-938.

Kuntzer, T., Bogousslavsky, J., Deruaz, J. P., Janzer, R., and Regli, F. Reversible emetine-induced myopathy with ECG abnormalities: a toxic myopathy. J Neurol. 1989;236(4):246-248.

Mateer, J. E., Farrell, B. J., Chou, S. S., and Gutmann, L. Reversible ipecac myopathy. Arch.Neurol. 1985;42(2):188-190.

Moldawsky, R. J. Myopathy and ipecac abuse in a bulimic patient. Psychosomatics 1985;26(5):448-449.

Kulig, K., Bar-Or, D., Cantrill, S. V., Rosen, P., and Rumack, B. H. Management of acutely poisoned patients without gastric emptying. Ann.Emerg.Med 1985;14(6):562-567.

Palmer, E. P. and Guay, A. T. Reversible myopathy secondary to abuse of ipecac in patients with major eating disorders. N.Engl.J.Med. 12-5-1985;313(23):1457-1459.

Mofenson, H. C. and Caraccio, T. R. Benefits/risks of syrup of ipecac. Pediatrics 1986;77(4):551-552.

Tandberg, D., Diven, B. G., and McLeod, J. W. Ipecac-induced emesis versus gastric lavage: a controlled study in normal adults. Am.J.Emerg.Med. 1986;4(3):205-209.

Auerbach, P. S., Osterloh, J., Braun, O., Hu, P., Geehr, E. C., Kizer, K. W., and McKinney, H. Efficacy of gastric emptying: gastric lavage versus emesis induced with ipecac. Ann.Emerg.Med. 1986;15(6):692-698.

Schiff, R. J., Wurzel, C. L., Brunson, S. C., Kasloff, I., Nussbaum, M. P., and Frank, S. D. Death due to chronic syrup of ipecac use in a patient with bulimia. Pediatrics 1986;78(3):412-416.

Rosenberg, N. L. and Ringel, S. P. Myopathy from surreptitious ipecac ingestion. West J.Med. 1986;145(3):386-388.

Freedman, G. E., Pasternak, S., and Krenzelok, E. P. A clinical trial using syrup of ipecac and activated charcoal concurrently. Ann.Emerg.Med. 1987;16(2):164-166.

Friedman, A. G., Seime, R. J., Roberts, T., and Fremouw, W. J. Ipecac abuse: a serious complication in bulimia. Gen.Hosp.Psychiatry 1987;9(3):225-228.

Knight, K. M. and Doucet, H. J. Gastric rupture and death caused by ipecac syrup. South.Med.J. 1987;80(6):786-787.

Tenenbein, M., Cohen, S., and Sitar, D. S. Efficacy of ipecac-induced emesis, orogastric lavage, and activated charcoal for acute drug overdose. Ann.Emerg.Med. 1987;16(8):838-841.

Halbig, L., Gutmann, L., Goebel, H. H., Brick, J. F., and Schochet, S. Ultrastructural pathology in emetine-induced myopathy. Acta Neuropathol. 1988;75(6):577-582.

Boxer, L., Anderson, F. P., and Rowe, D. S. Comparison of ipecac-induced emesis with gastric lavage in the treatment of acute salicylate ingestion. J.Pediatr. 1969;74(5):800-803.

MacLean, W. C., Jr. A comparison of ipecac syrup and apomorphine in the immediate treatment of ingestion of poisons. J.Pediatr. 1973;82(1):121-124.

Adler, A. G., Walinsky, P., Krall, R. A., and Cho, S. Y. Death resulting from ipecac syrup poisoning. JAMA 5-16-1980;243(19):1927-1928.

Brotman, M. C., Forbath, N., Garfinkel, P. E., and Humphrey, J. G. Myopathy due to ipecac syrup poisoning in a patient with anorexia nervosa. Can.Med.Assoc.J. 9-1-1981;125(5):453-454.

Bennett, H. S., Spiro, A. J., Pollack, M. A., and Zucker, P. Ipecac-induced myopathy simulating dermatomyositis. Neurology 1982;32(1):91-94.

Neuvonen, P. J., Vartiainen, M., and Tokola, O. Comparison of activated charcoal and ipecac syrup in prevention of drug absorption. Eur.J.Clin.Pharmacol. 1983;24(4):557-562.

Stewart, J. J. Effects of emetic and cathartic agents on the gastrointestinal tract and the treatment of toxic ingestion. J Toxicol.Clin Toxicol. 1983;20(3):199-253.

Curtis, R. A., Barone, J., and Giacona, N. Efficacy of ipecac and activated charcoal/cathartic. Prevention of salicylate absorption in a simulated overdose. Arch.Intern.Med 1984;144(1):48-52.

Luczynska, C. M., Marshall, P. E., Scarisbrick, D. A., and Topping, M. D. Occupational allergy due to inhalation of ipecacuanha dust. Clin.Allergy 1984;14(2):169-175.

Friedman, E. J. Death from ipecac intoxication in a patient with anorexia nervosa. Am.J.Psychiatry 1984;141(5):702-703.

Timberlake, G. A. Ipecac as a cause of the Mallory-Weiss syndrome. South.Med.J. 1984;77(6):804-805.

Wolowodiuk, O. J., McMicken, D. B., and O'Brien, P. Pneumomediastinum and retropneumoperitoneum: an unusual complication of syrup-of-ipecac-induced emesis. Ann.Emerg.Med. 1984;13(12):1148-1151.

Klein-Schwartz, W., Gorman, R. L., Oderda, G. M., Wedin, G. P., and Saggar, D. Ipecac use in the elderly: the unanswered question. Ann.Emerg.Med. 1984;13(12):1152-1154.

Schofferman, J. A. A clinical comparison of syrup of ipecac and apomorphine use in adults. JACEP. 1976;5(1):22-25.

Pond, S. M., Lewis-Driver, D. J., Williams, G. M., Green, A. C., and Stevenson, N. W. Gastric emptying in acute overdose: a prospective randomised controlled trial. Med J Aust 10-2-1995;163(7):345-349.

Olsen, K. M., Ma, F. H., Ackerman, B. H., and Stull, R. E. Low-volume whole bowel irrigation and salicylate absorption: a comparison with ipecac-charcoal. Pharmacotherapy 1993;13(3):229-232.

Bond, G. R., Requa, R. K., Krenzelok, E. P., Normann, S. A., Tendler, J. D., Morris, C. L., McCoy, D. J., Thompson, M. W., McCarthy, T., Roblez, J., and . Influence of time until emesis on the efficacy of decontamination using acetaminophen as a marker in a pediatric population. Ann.Emerg.Med 1993;22(9):1403-1407.

Young, W. F., Jr. and Bivins, H. G. Evaluation of gastric emptying using radionuclides: gastric lavage versus ipecac-induced emesis. Ann.Emerg.Med. 1993;22(9):1423-1427.

Phillips, S., Gomez, H., and Brent, J. Pediatric gastrointestinal decontamination in acute toxin ingestion. J Clin Pharmacol 1993;33(6):497-507.

Veltri, J. C. and Temple, A. R. Telephone management of poisonings using syrup of ipecac. Clin.Toxicol. 1976;9(3):407-417.

Thyagarajan, D., Day, B. J., Wodak, J., Gilligan, B., and Dennett, X. Emetine myopathy in a patient with an eating disorder. Med J Aust. 12-6-1993;159(11-12):757-760.

Schneider, D. J., Perez, A., Knilamus, T. E., Daniels, S. R., Bove, K. E., and Bonnell, H. Clinical and pathologic aspects of cardiomyopathy from ipecac administration in Munchausen's syndrome by proxy. Pediatrics 1996;97(6 Pt 1):902-906.

Lacomis, D. Case of the month. June 1996--anorexia nervosa. Brain Pathol. 1996;6(4):535-536.

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Andersen, J. M., Keljo, D. J., and Argyle, J. C. Secretory diarrhea caused by ipecac poisoning. J.Pediatr.Gastroenterol.Nutr. 1997;24(5):612-615.

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Ho, P. C., Dweik, R., and Cohen, M. C. Rapidly reversible cardiomyopathy associated with chronic ipecac ingestion. Clin.Cardiol. 1998;21(10):780-783.

Avau B, Borra V, Vanhove AC, Vandekerckhove P, De Paepe P, De Buck E. First aid interventions by laypeople for acute oral poisoning. Cochrane Database Syst Rev. 2018;12(12):CD013230.

Rossi AAB, de Oliveira LO, Venturini BA, dos Santos Silva R. Genetic diversity and geographic differentiation of disjunct Atlantic and Amazonian populations of Psychotria ipecacuanha (Rubiaceae). Genetica. 2009;136(1):57-67.

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