Irvine – Travel Guide At Wikivoyage

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Metrolink,☏ +1-800-371-5465.Runs commuter trains to/from downtown Los Angeles and San Bernardino via its Orange County and Inland Empire routes. Most trains continue to Laguna Niguel/Mission Viejo, and a few trains go as far as Oceanside in San Diego County. Depending on your intended destination, the 33.707938-117.805991 Tustin station may be closer than the 33.656802-117.7334682 Irvine Transportation Center.(updated Feb 2020)
Amtrak,☏ +11-800-872-7245.Pacific Surfliner trains also serve the Irvine Transportation Center (but not Tustin). Trains run between San Luis Obispo and San Diego via Los Angeles, and are more frequent than Metrolink on weekends.(updated Feb 2020)

Most buses serving the Irvine and Tustin train stations run only during peak commute hours on weekdays.