KEGG DISEASE: Viridans Group Streptococcal Infection

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KEGGDISEASE: Viridans group streptococcal infectionHelp
Entry
H01443 Disease
Name Viridans group streptococcal infection
Description The viridans group streptococci (VGS), a heterogenous group of streptococcal species, are the predominant species of the human oral flora and commonly inhabit other areas of the upper respiratory, gastrointestinal, and female genital tracts. VGS are usually organisms of low virulence. However, VGS are a major cause of sepsis and pneumonia in neutropenic individuals, and an important cause of sepsis and meningitis in neonates. These organisms are also occasional pathogens in healthy children and adults, causing infections such as subacute endocarditis. Although VGS resistance to penicillin and the macrolide-lincosamide-streptogramin B (MLS) drugs is an evolving problem, several drugs remain uniformly active against the VGS. Thus far, VGS resistance to vancomycin, linezolid, and daptomycin remains extremely rare.
Category Bacterial infectious disease
Brite Genome-based classification of infectious diseases [BR:br08401] Bacterial infections Infections caused by Gram-positive bacteria H01443 Viridans group streptococcal infection BRITE hierarchy
Pathogen Streptococcus mitisStreptococcus pseudopneumoniae [GN:std]Streptococcus sanguinis [GN:ssa]Streptococcus parasanguinis [GN:scf]Streptococcus gordonii [GN:sgo]Streptococcus constellatus [GN:scg scon scos]Streptococcus ilei [GN:sig sip]Streptococcus intermedius [GN:sib siu]Streptococcus anginosus [GN:sang sanc sans]Streptococcus mutans [GN:smu smc smut smj]Streptococcus sobrinusStreptococcus salivarius [GN:ssr stf]Streptococcus vestibularisStreptococcus thermophilusStreptococcus equinusStreptococcus gallolyticus [GN:sga sgg sgt]Streptococcus infantarius
Other DBs
MeSH: D013290
Reference PMID:20810781
Authors Doern CD, Burnham CA
Title It's not easy being green: the viridans group streptococci, with a focus on pediatric clinical manifestations.
Journal J Clin Microbiol 48:3829-35 (2010)DOI:10.1128/JCM.01563-10
Reference PMID:10720803
Authors Shenep JL
Title Viridans-group streptococcal infections in immunocompromised hosts.
Journal Int J Antimicrob Agents 14:129-35 (2000)DOI:10.1016/S0924-8579(99)00172-7
Reference PMID:17588233
Authors Reilly AF, Lange BJ
Title Infections with viridans group streptococci in children with cancer.
Journal Pediatr Blood Cancer 49:774-80 (2007)DOI:10.1002/pbc.21250
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