Methadone Detox: How Long Does It Take?

Because of the nature of methadone, the entire withdrawal and detox process can take significantly longer than with other opioids and other addictive substances. Symptoms can begin within the first 24 hours after you used methadone last, and the entire withdrawal process can last up to several weeks, depending on the severity of the addiction. Here is a breakdown of what you can expect during the first few weeks of the methadone withdrawal timeline:

Days 1 and 2

With the initial withdrawal symptoms not typically showing up for at least 24 hours after the last dose is taken, the first two days tend to be pretty normal. During the first two days, you may begin to experience the following symptoms:

• Muscle aches
• Rapid heartbeat
• Fever
• Chills

Days 3 through 8

It’s during this time period when the methadone withdrawal symptoms will typically hit their peak. Depending on the severity of the addiction, the symptoms can be anywhere from relatively mild to extreme. This is also the time period when cravings will be the strongest. In addition to the symptoms that you might have begun feeling during the first two days, additional symptoms that you may experience during days 3 through 8 include:

• Anxiety
• Body aches
• Nausea
• Irritability,
• Insomnia
• Depression
• Vomiting
• Cramps
• Flu-like physical symptoms

Days 9 through 15

Once you have hit day 9, you will likely notice that some of the symptoms have begun to subside. However, that doesn’t mean that you are in the clear yet. During this time, you will likely still experience some of the following symptoms:

• Strong cravings
• Physical discomfort
• Irritability
• Diarrhea
• Depression

Days 15 and On

Symptoms such as strong cravings, low energy levels, and trouble sleeping can persist for weeks after you have stopped taking methadone. In addition, in the weeks and months after stopping taking methadone, many people have reported experiencing post-acute withdrawal symptoms, otherwise known as PAWS. Those experiencing PAWS may continue to do so for months or even years after they have stopped taking methadone.

Some common symptoms associated with post-acute withdrawal include:

• Inability to feel pleasure
• Trouble sleeping
• Poor concentration
• Depression
• Anxiety
• Irritability

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