Noxipak (Fluocinolone Acetonide Topical Solution) - RxList

What Is Noxipak?

Noxipak (fluocinolone acetonide and urea kit) is a combination of a corticosteroid and a keratolytic used to manage hypertrophic tissues, keloid tissues, dermatitis, and dermatoses.

What Are Side Effects of Noxipak?

Common side effects of Noxipak include:

• burning,
• itching,
• irritation,
• dryness,
• hair bumps,
• abnormal hair growth
• acne,
• loss of pigmentation,
• sores around the mouth,
• allergic contact dermatitis,
• softening and breakdown of the skin,
• secondary infection,
• skin atrophy,
• stretch marks, and
• sweat rash

Seek medical care or call 911 at once if you have the following serious side effects:

• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheadedness, or passing out;
• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Noxipak

First apply fluocinolone acetonide 0.01% topical solution to the affected area, rub into skin until absorbed. Then apply urea 20% cream and rub into skin until completely absorbed. Apply twice a day or as directed by your physician. Cover the affected area with silicone tape at bedtime or as directed by your physician.

Noxipak In Children

Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome than mature patients because of a larger skin surface area to body weight ratio.

Hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome, and intracranial hypertension have been reported in children receiving topical corticosteroids. Manifestations of adrenal suppression in children include linear growth retardation, delayed weight gain, low plasma cortisol levels, and absence of response to ACTH stimulation. Manifestations of intracranial hypertension include bulging fontanelles, headaches, and bilateral papilledema.

Administration of topical corticosteroids to children should be limited to the least amount compatible with an effective therapeutic regimen. Chronic corticosteroid therapy may interfere with the growth and development of children.

What Drugs, Substances, or Supplements Interact with Noxipak?

Noxipak may interact with other medicines.

Tell your doctor all medications and supplements you use.

Noxipak During Pregnancy and Breastfeeding

Our Noxipak (fluocinolone acetonide and urea kit) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

Additional Information

Our Noxipak 101 Gas (nitric oxide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.