Plasma: The Need For Donors & What You Can Do To Help

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Plasma: The Need for Donors & What You Can Do to Help
December 9, 2025 All, Immunology Admin Plasma: The Need for Donors & What You Can Do to Help
America needs blood and plasma donors.

This article discusses what plasma is, the important functions it serves, and who’s eligible to donate.

Plasma is the liquid part of your blood that carries cells and proteins throughout the body. It’s made up of mostly water (92%+), but contains vital proteins and antibodies such as albumin, gamma globulin, and anti-hemophilic factor along with mineral salts, sugars, fats, hormones, vitamins, carbon dioxide, and oxygen.

According to The American Red Cross, plasma serves four important functions in our bodies:

  1. Helps maintain blood pressure and volume

  2. Supplies critical proteins for blood clotting and immunity against certain diseases

  3. Carries electrolytes such as sodium and potassium to our muscles

  4. Helps maintain a proper pH balance in the body, which supports cell function

The Plasma Protein Therapeutics Association (PPTA) says that “plasma-derived medicines are high-impact pharmaceuticals because they increase life expectancy, improve quality of life, and reduce life-threatening complications for individuals with plasma protein deficiencies. Plasma-derived medicines provide immeasurable, lifelong benefits to the patients who use them.”

Donated plasma is typically used to manufacture therapies to treat people with (but not limited to):

  • Bleeding disorders

  • Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

  • Primary Immunodeficiency Disease (PIDD)

  • Idiopathic Thrombocytpenic Purpura (ITP)

  • Kawasaki Disease

  • Cancer

  • Organ transplant recipients

  • Severe liver disease

  • Trauma and burns

Our infusion pharmacy manages several medications manufactured from plasma. These treatments include Immune Globulin (IG) for neurology, immunology, and transplant patients as well as factor replacement products for bleeding disorders.

The Growing Need for Plasma

Because of the number of people who rely on plasma for medical treatment, there has been a growing need for years.

Nearly 5,000 units of platelets and 6.500 units of plasma are needed daily in the U.S.

Who is Eligible to Donate Plasma?

The FDA provides guidelines for eligibility here.

In general, you must be at least 18 yrs old, weigh at least 110 lbs, and be in general good health. As a new donor, you must also possess and present both a document with your Social Security number or an INS number and a valid picture ID (driver’s license, student or military ID) with your current local address. There may be some additional restrictions preventing you from donating such as recent tattoos, body piercings, prolonged residence in certain parts of the world, and/or other medical conditions. Check with your local donation center regarding restrictions or questions regarding your ability to donate.

It’s also important to note that as a new donor, you must donate twice within 6 months for your plasma to be used.

Both donations must pass certain tests and screenings needed to assure the safety and quality of the supply. Because of the time commitment it takes to donate plasma, plasma donation is eligible for compensation. The amount of compensation depends on the donation center.

If you have type AB blood, the American Red Cross urges you to donate. AB is the only universal plasma that can be given to patients of any blood type. It can be given to patients immediately without determining compatibility. This time saved can mean the difference between life and death.

Type AB plasma donations – which the Red Cross calls “AB Elite” – can be made every 28 days, up to 13 times per year. The average donation takes one hour and 15 minutes, just a few minutes longer than donating whole blood.

Where Can I Donate Plasma?

To find a plasma donation center in your area, click the button below to visit donatingplasma.org.

Find A Plasma Donation Center

DISCLAIMER: THIS IS NOT MEDICAL OR LEGAL ADVICE. All information, content, and material is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider or as legal advice. Please consult a physician or other health care professional for your specific health care and/or medical needs or concerns and never disregard professional medical advice or delay in seeking it because of something you have read here or on our website.

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