Snorting Melatonin: Side Effects, Risks, And Dangers

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answered by Treatment X Evidence Based Snorting Melatonin: Side Effects, Risks, And Dangers Written by Dr. Anjali Talcherkar, Ph.D. Medically Reviewed by Johnelle Smith, M.D.

Updated on September 3, 2025

Melatonin is a beneficial natural hormone that can be helpful in the treatment of sleep disorders, and some people use melatonin to manage drug withdrawal symptoms. Snorting melatonin in any form is dangerous and should be avoided.

ON THIS PAGE:
  • Why Snort Melatonin?
  • Effects Of Snorting Melatonin
  • Is Melatonin Addictive?
  • Treatment For Melatonin Addiction
  • Show More
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Melatonin is a natural hormone made by a small gland in your brain called the pineal gland. This hormone helps control your sleep cycle by telling your body when it’s time to feel sleepy and when to wake up. It works with your body’s internal clock to keep your sleep schedule on track.

You can buy melatonin supplements at most stores without a prescription to help with sleep problems or to reduce withdrawal symptoms when quitting smoking or certain medications, such as benzodiazepines. However, some people try to snort melatonin powder thinking it will work faster or stronger. This dangerous practice can cause serious health problems and is not how melatonin is meant to be used.

Why Would A Person Snort Melatonin?

People might snort melatonin if they were using it to treat anxiety, depression, or symptoms associated with benzodiazepine withdrawal symptoms and detoxification.

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People often believe that snorting a drug creates faster uptake and more intense effects. This is generally true for some drugs which can be absorbed through the nasal passage ways. However, snorting melatonin is harmful to the body and has not been proven to increase the substance’s effects. It is most effectively taken sublingually or in pill form. People may take it in conjunction with other sedatives or central nervous system depressants, which can have dangerous results.

Effects Of Snorting Crushed Up Melatonin Pills

Snorting melatonin is both dangerous and pointless. This method doesn’t make the supplement work better or faster, but it can cause serious harm to your nose, throat, and face. When you put crushed pills or powder into your nasal passages, you’re introducing harmful substances that your nose wasn’t designed to handle.

Physical side effects of snorting crushed up melatonin may include:

  • trouble swallowing
  • throat damage
  • ear pain
  • facial swelling and pain
  • nose bleeds
  • damage to the nasal cavity and septum
  • damage to nasal passages
  • nasal congestion
  • constantly runny nose
  • oral ulcers
  • trouble speaking

The risks of snorting melatonin far outweigh any imagined benefits. These physical side effects can be painful, long-lasting, and may require medical treatment to heal. Melatonin works best when taken as directed, and snorting it only puts your health in danger.

Is Melatonin Addictive?

Melatonin is not known to be addictive or cause dependence or withdrawal symptoms. This is why it is considered preferable to many prescription sleep aids.

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People regard melatonin positively because there are very few negative effects when used appropriately, especially since it doesn’t tend to create tolerance or a sleep “hangover” in people. While melatonin can be used safely in a regulated manner, the Food and Drug Administration (FDA) does not regulate these pills as strenuously as over-the-counter medications. Melatonin use, especially as a self-medication or recreational substance, can still have negative side effects and be dangerous if used to intensify other drugs.

Written by the Addiction Resource Editorial Staff

This page does not provide medical advice. See more Article resources

Addiction Resource aims to provide only the most current, accurate information in regards to addiction and addiction treatment, which means we only reference the most credible sources available.

These include peer-reviewed journals, government entities and academic institutions, and leaders in addiction healthcare and advocacy. Learn more about how we safeguard our content by viewing our editorial policy.

  • Medscape – Melatoninhttps://reference.medscape.com/drug/n-acetyl-5-methoxytryptamine-pineal-hormone-melatonin-melatonin-344545
  • World Journal of Psychiatry – Melatonin in drug addiction and addiction management: Exploring an evolving multidimensional relationshiphttps://pmc.ncbi.nlm.nih.gov/articles/PMC6033744/
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