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Viral Envelope Proteins

"Viral Envelope Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information Definition | Details | More General Concepts | Related Concepts | More Specific Concepts Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. The outer layer consists of one or more types of morphological subunits called peplomers which project from the viral envelope; this layer always consists of glycoproteins.

Descriptor ID	D014759
MeSH Number(s)	D12.776.964.970.880
Concept/Terms	Viral Envelope Proteins Viral Envelope Proteins Proteins, Viral Envelope Virus Envelope Proteins Envelope Proteins, Virus Proteins, Virus Envelope Envelope Proteins, Viral Coronavirus gpE1 Coronavirus gpE1 Coronavirus Peplomer Protein E1 Coronavirus Peplomer Protein E1 Coronavirus Peplomer Protein E2 JHM Coronavirus Peplomer Protein E2 JHM Hepatitis Virus (MHV) Glycoprotein E2 Hepatitis Virus (MHV) Glycoprotein E2 LaCrosse Virus Envelope Glycoprotein G1 LaCrosse Virus Envelope Glycoprotein G1 Simian Sarcoma Virus Glycoprotein 70 Simian Sarcoma Virus Glycoprotein 70 Viral Envelope Glycoprotein gp55 (Friend Virus) Viral Envelope Glycoprotein gp55 (Friend Virus) Viral Envelope Glycoprotein gPr90 (Murine Leukemia Virus) Viral Envelope Glycoprotein gPr90 (Murine Leukemia Virus) Viral Envelope Proteins E1 Viral Envelope Proteins E1 Viral Envelope Proteins E2 Viral Envelope Proteins E2 Viral Envelope Proteins gp52 Viral Envelope Proteins gp52 Viral Envelope Proteins gp70 Viral Envelope Proteins gp70 Virus Peplomer Proteins Virus Peplomer Proteins Peplomer Proteins, Virus Proteins, Virus Peplomer Bovine Leukemia Virus Glycoprotein gp51 Bovine Leukemia Virus Glycoprotein gp51 Corona Virus Membrane Protein E1 Corona Virus Membrane Protein E1

Below are MeSH descriptors whose meaning is more general than "Viral Envelope Proteins".

• Chemicals and Drugs [D]
• Amino Acids, Peptides, and Proteins [D12]
• Proteins [D12.776]
• Viral Proteins [D12.776.964]
• Viral Structural Proteins [D12.776.964.970]
• Viral Envelope Proteins [D12.776.964.970.880]

Below are MeSH descriptors whose meaning is related to "Viral Envelope Proteins".

• Viral Structural Proteins
• Nucleocapsid Proteins
• Plant Viral Movement Proteins
• Viral Envelope Proteins
• Viral Tail Proteins

Below are MeSH descriptors whose meaning is more specific than "Viral Envelope Proteins".

• Viral Envelope Proteins
• Gene Products, env
• Hemagglutinins, Viral
• HN Protein
• Viral Fusion Proteins
• Viral Matrix Proteins

publications Timeline | Most Recent This graph shows the total number of publications written about "Viral Envelope Proteins" by people in this website by year, and whether "Viral Envelope Proteins" was a major or minor topic of these publications. To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1998	1	1	2
1999	0	1	1
2000	1	0	1
2002	1	0	1
2003	0	2	2
2004	2	1	3
2005	2	3	5
2007	1	3	4
2008	1	0	1
2009	3	3	6
2010	2	2	4
2011	4	3	7
2012	3	2	5
2013	0	2	2
2014	1	0	1
2015	1	0	1
2016	2	2	4
2017	0	2	2
2018	0	2	2
2019	1	1	2
2020	3	0	3
2021	2	1	3
2022	0	2	2
2023	0	1	1
2024	1	0	1
2025	1	0	1

To return to the timeline, click here. Below are the most recent publications written about "Viral Envelope Proteins" by people in Profiles.

1. Durham ND, Jain A, Howard A, Luban J, Munro JB. Molecular basis for the increased fusion activity of the Ebola virus glycoprotein epidemic variant A82V: Insights from simulations and experiments. Cell Rep. 2025 Apr 22; 44(4):115521. View in: PubMed
2. Cua S, Tello BA, Farelo MA, Rodriguez E, Escalante GM, Mutsvunguma LZ, Ogembo JG, Reidel IG. A Novel Monoclonal Antibody Against a Modified Vaccinia Ankara (MVA) Envelope Protein as a Tool for MVA Virus Titration by Flow Cytometry. Viruses. 2024 10 17; 16(10). View in: PubMed
3. Muniraju M, Mutsvunguma LZ, Reidel IG, Escalante GM, Cua S, Musonda W, Calero-Landa J, Farelo MA, Rodriguez E, Li Z, Ogembo JG. Kaposi sarcoma-associated herpesvirus complement control protein (KCP) and glycoprotein K8.1 are not required for viral infection in vitro or in vivo. J Virol. 2024 Jun 13; 98(6):e0057624. View in: PubMed
4. Vaknin A, Grossman A, Durham ND, Lupovitz I, Goren S, Golani G, Roichman Y, Munro JB, Sorkin R. Ebola Virus Glycoprotein Strongly Binds to Membranes in the Absence of Receptor Engagement. ACS Infect Dis. 2024 05 10; 10(5):1590-1601. View in: PubMed
5. Jain A, Govindan R, Berkman AR, Luban J, D?az-Salinas MA, Durham ND, Munro JB. Regulation of Ebola GP conformation and membrane binding by the chemical environment of the late endosome. PLoS Pathog. 2023 Dec; 19(12):e1011848. View in: PubMed
6. Willett BJ, Grove J, MacLean OA, Wilkie C, De Lorenzo G, Furnon W, Cantoni D, Scott S, Logan N, Ashraf S, Manali M, Szemiel A, Cowton V, Vink E, Harvey WT, Davis C, Asamaphan P, Smollett K, Tong L, Orton R, Hughes J, Holland P, Silva V, Pascall DJ, Puxty K, da Silva Filipe A, Yebra G, Shaaban S, Holden MTG, Pinto RM, Gunson R, Templeton K, Murcia PR, Patel AH, Klenerman P, Dunachie S, Haughney J, Robertson DL, Palmarini M, Ray S, Thomson EC. SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nat Microbiol. 2022 08; 7(8):1161-1179. View in: PubMed
7. Brehm TT, Pfefferle S, von Possel R, Karolyi M, Zoufaly A, Wichmann D, Kobbe R, Emmerich P, N?rz D, Aepfelbacher M, Schulze Zur Wiesch J, Addo MM, Schmiedel S, L?tgehetmann M. Clinical efficacy and in vitro neutralization capacity of monoclonal antibodies for severe acute respiratory syndrome coronavirus 2 delta and omicron variants. J Med Virol. 2022 10; 94(10):5038-5043. View in: PubMed
8. Diehl WE, Guney MH, Vanzo T, Kyawe PP, White JM, Pizzato M, Luban J. Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity. Viruses. 2021 06 30; 13(7). View in: PubMed
9. Wang HY, Valencia SM, Pfeifer SP, Jensen JD, Kowalik TF, Permar SR. Common Polymorphisms in the Glycoproteins of Human Cytomegalovirus and Associated Strain-Specific Immunity. Viruses. 2021 06 09; 13(6). View in: PubMed
10. Murray LP, Govindan R, Mora AC, Munro JB, Mace CR. Antibody affinity as a driver of signal generation in a paper-based immunoassay for Ebola virus surveillance. Anal Bioanal Chem. 2021 Jun; 413(14):3695-3706. View in: PubMed

People People who have written about this concept.

• Munro, James
• Durham, Natasha
• Luban, Jeremy
• Wang, Yang
• Lu, Shan

Explore _ Similar Concepts Similar concepts derived from published works.

• Membrane Fusion
• Virion
• Virus Internalization
• env Gene Products, Human Immunodeficiency Virus
• Hemorrhagic Fever, Ebola
• HIV Antibodies
• HIV-1
• Protein Conformation
• Spike Glycoprotein, Coronavirus
• Ebolavirus

_ Top Journals Top journals in which articles about this concept have been published.

• J Virol
• Virology
• Viruses
• Virus Res
• Antiviral Res
• Proc Natl Acad Sci U S A
• J Infect Dis
• J Biol Chem
• Science
• AIDS Res Hum Retroviruses