The placenta as a barrier for toxic and essential elements in paired ... pubmed.ncbi.nlm.nih.gov › ...
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6 Jan 2015 · Zofran (ondansetron) has properties that cause it to easily cross the placenta in substantial amounts. Just for example, it has great lipid ...
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30 May 2014 · Most drugs (especially type 1 drugs) cross the placenta by this mechanism. Transfer is either transcellularly through the syncytiotrophoblast ... Placental structure · Functions of the placenta · Placental drug transfer
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Yet, most drugs that enter the maternal circulation can cross the placenta to some extent (Unadkat et al., 2004). Passive diffusion ... Abstract · Introduction · The Placental Barrier · Conclusion
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Any chemical with a molecular weight (MW) <1000 readily crosses the placenta, and most drugs of use and abuse, pesticides, metals, mycotoxins, plant alkaloids, ...
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Maternal hormones therefore play a very limited role in the fetal endocrine milieu. Hormones that do cross the placenta may be metabolized en route (Fig. 23.1), ...
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Most drugs with MW < 500 Da cross the placenta, and most drugs with MW > 1000 Da do not cross the placenta (ex. heparin, protamine, insulin). Neither ...
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16 Aug 2019 · Based on the physiology of the placenta, the placental barrier is structurally defined by the placental trophoblast and fetal capillary ...
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The toxic effects of most drugs are well known. Not as well defined are the ability of a particular drug to cross the placental barrier and the drug's fetal ...
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21 Dec 2020 · Their early findings, from COVID-19-positive women who gave birth in April and May 2020, indicate that the virus can penetrate the placenta, but ...
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Throughout pregnancy, the placenta acts as a physical and immunological barrier against the hematogenous transmission of viruses from mother to fetus.
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6 Aug 2000 · In addition to transporting some molecules unaltered between fetal and maternal blood, it also consumes a large fraction of certain types of ...
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This is the first time the molecular mechanism allowing a pathogenic bacterium to cross the placenta in vivo is discovered. This work is published on September ...
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immunoglobulins - IgA and IgM are excluded from crossing the placenta. · conjugated bilirubin only crosses the placenta slowly from fetus to mother. · warfarin ...
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5 Jan 2021 · This abnormality may cause the coronavirus-specific antibodies to get stuck in the maternal circulation because they cannot bind as well to ...
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