Mar 3, 2020
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E-cadherin tumor suppressor genes are particularly active area of research in development and tumorigenesis. The calcium-dependent interactions among ... E-cadherin gene and protein... · Role of E-cadherin in normal... · Mutation reports
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Jun 28, 2001 · E-cadherin is a glycoprotein with a large extracellular domain comprising five cadherin-motif subdomains, a single-pass transmembrane segment ...
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Jun 5, 2021 · Molecular mechanisms for impaired E-Cadherin function include inactivating gene mutations, chromosomal deletions, and promotor hypermethylation ...
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Apr 26, 2018 · E-cadherin (CDH1) is a putative tumor suppressor gene implicated in breast carcinogenesis. Yet, whether risk factors or survival differ by ...
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Sep 4, 2019 · Here we show that E-cadherin promotes metastasis in diverse models of invasive ductal carcinomas. While loss of E-cadherin increased invasion, ...
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Jul 19, 2021 · Cadherin which is a type of cell surface transmembrane glycoprotein has an important influence on the cell-cell adhesion function. E-cadherin ...
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May 15, 2008 · One protein prominently associated with tumor invasiveness, metastatic dissemination, and poor patient prognosis is the epithelial cell adhesion ...
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The loss of E-cadherin expression was strongly correlated with lymph node metastasis. The odds that an E-cadherin negative subject would also exhibit positive ...
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Aug 1, 2017 · E-cadherin is one of the best-understood cadherin proteins. In addition to its role in cell adhesion, E-cadherin is involved in transmitting ...
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E-cadherin is a tumor suppressor protein with a well-established role in cell–cell adhesion. Adhesion could contribute to tumor suppression either by ...
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Aug 31, 2016 · E-cadherin–mediated cell adhesion is often believed to affect tumor invasion by inhibiting cell migration away from the epithelial layer.
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Background/Aim: E-Cadherin is a marker with a controversial function. Its role is often interpreted in the context of the epithelial-mesenchymal transition. In ...
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The loss of E-cadherin is one of the key hallmarks of epithelial-to-mesenchymal transition, a biological process that promotes cancer cell invasiveness and ...
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E-cadherin is a calcium-dependent cell adhesion molecule that is normally expressed at adherent junctions between epithelial cells. The linkage of E-cadherin by ...
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