Top Most 23+ What Is Anti Sm Antibody
-
1.Whither Smooth Muscle Antibodies In The Third Millennium? | Journal Of Clinical Pathology
-
2.AB0525 ANTI-SMITH ANTIBODY IS ASSOCIATED WITH DISEASE ACTIVITY IN PATIENTS WITH NEW-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS | Annals Of The Rheumatic Diseases
-
3.Anti-Smith Antibody Is Associated With Disease Activity In Patients With New-onset Systemic Lupus Erythematosus - PubMed
Although anti-Smith (Sm) antibody is a highly specific antibody for systemic lupus erythematosus (SLE), the significance of anti-Sm antibody in patients with SLE is unclear. This study aimed to evaluate the association between anti-Sm antibodies and disease activity in patients with new-onset SLE. W …
View more » -
4.Anti-Smith Antibody: Reference Range, Interpretation, Collection/Panels
Anti-Smith antibodies are present in some cases of systemic lupus erythematosus (SLE) and mixed connective-tissue disease (MCTD). The reference range of anti-Smith antibodies is negative.
View more » -
5.Anti-Smith Antibody: Reference Range, Interpretation, Collection/Panels
Anti-Smith antibodies are present in some cases of systemic lupus erythematosus (SLE) and mixed connective-tissue disease (MCTD). The reference range of anti-Smith antibodies is negative.
View more » -
6.Anti-Smith Antibody: Reference Range, Interpretation, Collection/Panels
Anti-Smith antibodies are present in some cases of systemic lupus erythematosus (SLE) and mixed connective-tissue disease (MCTD). The reference range of anti-Smith antibodies is negative.
View more » -
7.Anti-Smith Antibody: Reference Range, Interpretation, Collection/Panels
Anti-Smith antibodies are present in some cases of systemic lupus erythematosus (SLE) and mixed connective-tissue disease (MCTD). The reference range of anti-Smith antibodies is negative.
View more » -
8.SM - Overview: Sm Antibodies, IgG, Serum
-
9.Anti-smooth Muscle Antibody Information | Mount Sinai - New York
Learn about Anti-smooth muscle antibody, find a doctor, complications, outcomes, recovery and follow-up care for Anti-smooth muscle antibody.
View more » -
10.Anti-smooth Muscle Antibody Information | Mount Sinai - New York
Learn about Anti-smooth muscle antibody, find a doctor, complications, outcomes, recovery and follow-up care for Anti-smooth muscle antibody.
View more » -
11.Anti-smooth Muscle Antibody Information | Mount Sinai - New York
Learn about Anti-smooth muscle antibody, find a doctor, complications, outcomes, recovery and follow-up care for Anti-smooth muscle antibody.
View more » -
12.Anti-smooth Muscle Antibody Information | Mount Sinai - New York
Learn about Anti-smooth muscle antibody, find a doctor, complications, outcomes, recovery and follow-up care for Anti-smooth muscle antibody.
View more » -
13.Sm Antibodies, IgG, Serum - Mayo Clinic Laboratories | Neurology Catalog
-
14.Anti-SM Antibody - South Tees Hospitals NHS Foundation Trust
Description Small nuclear RNP (snRNP) particles often termed spliceosomes are composed of small RNA molecules, together with associated proteins including snRNPs which contain an Sm core together with proteins which are specific to that type of particle. The well-characterised RNP autoantigens are located primarily in U1 snRNP complexes where they are involved in pre-mRNA splicing. […]
View more » -
15.Identification Of A SmD3 Epitope With A Single Symmetrical Dimethylation Of An Arginine Residue As A Specific Target Of A Subpopulation Of Anti-Sm Antibodies - Arthritis Research & Therapy
Anti-Sm antibodies, identified in 1966 by Tan and Kunkel, are highly specific serological markers for systemic lupus erythrematosus (SLE). Anti-Sm reactivity is found in 5–30% of SLE patients, depending on the autoantibody detection system and the racial background of the SLE population. The Sm autoantigen complex comprises at least nine different polypeptides. All of these core proteins can serve as targets of the anti-Sm B-cell response, but most frequently the B and D polypeptides are involved. Because the BB'Sm proteins share cross-reactive epitopes (PPPGMRPP) with U1 specific ribonucleoproteins, which are more frequently targeted by antibodies that are present in patients with mixed connective tissue disease, the SmD polypeptides are regarded as the Sm autoantigens that are most specific to SLE. It was recently shown that the polypeptides D1, D3 and BB' contain symmetrical dimethylarginine, which is a component of a major autoepitope within the carboxyl-terminus of SmD1. In one of those studies, a synthetic dimethylated peptide of SmD1 (amino acids 95–119) exhibited significantly increased immunoreactivity as compared with unmodified SmD1 peptide. Using immobilized peptides, we confirmed that the dimethylated arginine residues play an essential role in the formation of major SmD1 and SmD3 autoepitopes. Moreover, we demonstrated that one particular peptide of SmD3 represents a more sensitive and more reliable substrate for the detection of a subclass of anti-Sm antibodies. Twenty-eight out of 176 (15.9%) SLE patients but only one out of 449 (0.2%) control individuals tested positive for the anti-SmD3 peptide (SMP) antibodies in a new ELISA system. These data indicate that anti-SMP antibodies are exclusively present in sera from SLE patients. Thus, anti-SMP detection using ELISA represents a new serological marker with which to diagnose and discriminate between systemic autoimmune disorders.
View more » -
16.Understanding Lupus Lab Tests And Results | Rheumatology
Understanding Lupus Lab Tests and Results | Rheumatology
View more » -
17.Lupus Blood Tests : Johns Hopkins Lupus Center
Blood Tests Used in the Diagnosis of Lupus Antibodies form in the body as a response to infection. When an invader (antigen) enters the body, white blood
View more » -
18.Anti-Smith Antibody Positivity Without Lupus In The Setting Of Lung Cancer
The interpretation of positive serologic findings in cancer sera remains controversial. Selected antinuclear antibodies (ANAs), such as anti-double-stranded deoxyribonucleic acid (dsDNA) and anti-Smith, are highly specific for the diagnosis of systemic lupus erythematosus (SLE). On the other hand, the ANA titer is sensitive but not specific for SLE and has been reported in healthy individuals, various infections, other autoimmune diseases and cancer. We report for the first time positive anti-Smith antibody in two patients without lupus in the setting of lung cancer.
View more » -
19.Title
-
20.Anti-Smith Antibody
AKA: Anti-Smith Antibody / Sm / Anti-Sm antibodies / Smith (ENA) Antibody, IgG The Anti-Smith Antibody&nbs...
View more » -
21.UpToDate
{{configCtrl2.info.metaDescription}}
View more » -
22.520013: Anti-Sm Ab (RDL) | Labcorp
Labcorp test details for Anti-Sm Ab (RDL)
View more » -
23.Anti-Sm | Autoimmundiagnostik: Test Für Die SLE-Diagnostik / Prognose (ACR Kriterien!)
Anti-Sm von ORGENTEC Diagnostika ermöglicht den sicheren und spezifischen Nachweis von Autoantikörpern, unter anderem bei Verdacht auf systemischen Lupus erythematodes, SLE. Die Anti-Sm-Antikörper sind ein Marker für diese autoimmune Erkrankung, ihr Nachweis ein anerkanntes SLE-Diagnosekriterium (ACR-Kriterien).
View more »