Since the introduction of the Cockcroft-Gault equation to calculate creatinine clearance, there has been debate about which weight to use in the equation.
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Creatinine Clearance Methods including Jelliffe method, cockcroft and gault. CrCL calculator based on the cockcroft and gault equation
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We propose the use of a CrCl range for drug dosing purposes, with the lower boundary defined by using IBW in the Cockcroft-Gault equation and the upper boundary by using TBW.
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Using the Cockcroft-Gault equation with no body weight and actual S(cr) value most closely estimated measured Cl(cr). In obese patients, it may be reasonable to use actual body weight with a correction factor of 0.3 or 0.4 and actual S(cr) value in the Cockcroft-Gault equation. Based on this analysi …
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Prescribing medicines in renal impairment
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