2022 ICD-10-CM Diagnosis Code C50.4: Malignant Neoplasm Of ...

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2026

  1. ICD-10-CM Codes
    2. ›
  2. C00-D49
    3. ›
  3. C50-C50
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  4. C50-
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  5. 2026 ICD-10-CM Diagnosis Code C50.4
2026 ICD-10-CM Diagnosis Code C50.4

Malignant neoplasm of upper-outer quadrant of breast

    2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 Non-Billable/Non-Specific Code
  • C50.4 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2026 edition of ICD-10-CM C50.4 became effective on October 1, 2025.
  • This is the American ICD-10-CM version of C50.4 - other international versions of ICD-10 C50.4 may differ.
The following code(s) above C50.4 contain annotation back-referencesAnnotation Back-ReferencesIn this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to C50.4:
  • C00-D49 2026 ICD-10-CM Range C00-D49

    NeoplasmsNote
    • Functional activity
    • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
    • Morphology [Histology]
    • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
    • Primary malignant neoplasms overlapping site boundaries
    • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
    • Malignant neoplasm of ectopic tissue
    • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
    Neoplasms

  • C50 ICD-10-CM Diagnosis Code C50

    Malignant neoplasm of breast

      2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 Non-Billable/Non-Specific Code
    Includes
    • connective tissue of breast
    • Paget's disease of breast
    • Paget's disease of nipple
    Type 1 Excludes
    • skin of breast (C44.501, C44.511, C44.521, C44.591)
    Use Additional
    • code to identify estrogen, and other hormones and factors receptor status (Z17.-)
    Malignant neoplasm of breast
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change
  • 2026 (effective 10/1/2025): No change
ICD-10-CM Codes Adjacent To C50.4 C50.229 Malignant neoplasm of upper-inner quadrant of unspecified male breast C50.3 Malignant neoplasm of lower-inner quadrant of breast C50.31 Malignant neoplasm of lower-inner quadrant of breast, female C50.311 Malignant neoplasm of lower-inner quadrant of right female breast C50.312 Malignant neoplasm of lower-inner quadrant of left female breast C50.319 Malignant neoplasm of lower-inner quadrant of unspecified female breast C50.32 Malignant neoplasm of lower-inner quadrant of breast, male C50.321 Malignant neoplasm of lower-inner quadrant of right male breast C50.322 Malignant neoplasm of lower-inner quadrant of left male breast C50.329 Malignant neoplasm of lower-inner quadrant of unspecified male breast C50.4 Malignant neoplasm of upper-outer quadrant of breast C50.41 Malignant neoplasm of upper-outer quadrant of breast, female C50.411 Malignant neoplasm of upper-outer quadrant of right female breast C50.412 Malignant neoplasm of upper-outer quadrant of left female breast C50.419 Malignant neoplasm of upper-outer quadrant of unspecified female breast C50.42 Malignant neoplasm of upper-outer quadrant of breast, male C50.421 Malignant neoplasm of upper-outer quadrant of right male breast C50.422 Malignant neoplasm of upper-outer quadrant of left male breast C50.429 Malignant neoplasm of upper-outer quadrant of unspecified male breast C50.5 Malignant neoplasm of lower-outer quadrant of breast C50.51 Malignant neoplasm of lower-outer quadrant of breast, female

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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