Production of 4-Methylacetophenone 4-Methylacetophenone is prepared by acylation of tolune using Freidel Crafts acylation. It is performed by slow addition of acetyl chloride to a mixture of toluene and AlCl in an ice bath and under vacuum, maintaining the temperature at +5°C and then letting it increase to +20°C. This creates a mixture of 2-, 3- and 4- isomer which is then separated. ASTM Testing Standard • D3437 Practice for Sampling and Handling Liquid Cyclic Products • D4307 Practice for Preparation of Liquid Blends for Use as Analytical Standards • D4790 Terminology of Aromatic Hydrocarbons and Related Chemicals • D6809 Guide for Quality Control and Quality Assurance Procedures for Aromatic Hydrocarbons and Related Materials • E29 Practice for Using Significant Digits in Test Data to Determine Conformance with Specifications • E355 Practice for Gas Chromatography Terms and Relationships • E691 Practice for Conducting an Interlaboratory Study to Determine the Precision of a Test Method • E1510 Practice for Installing Fused Silica Open Tubular Capillary Columns in Gas Chromatographs Storage and Handling Handling: • Wash thoroughly after handling. • Remove contaminated clothing and wash before reuse. • Avoid contact with eyes, skin, and clothing. • Empty containers retain product residue, and can be dangerous. Keep container tightly closed. • Avoid ingestion and inhalation. • Avoid breathing spray or mist. Storage: • Keep away from sources of ignition. • Store in a tightly closed container. • Store in a cool, dry, well-ventilated area away from incompatible substances. Incompatible Materials Acids, Acid chlorides, Acid anhydrides, Oxidizing agents Fire Fighting • Wear a self-contained breathing apparatus in pressure-demand and full protective gear. • During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. • Use water spray to keep fire-exposed containers cool. • Combustible liquid and vapor. • Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam. First Aid • Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid. Hazard Statement • Harmful if swallowed • Flammable solid • Keep away from heat/sparks/open flames/hot surfaces. — No smoking • Potential Health Effects • Eye: May cause eye irritation. • Skin: May cause skin irritation. • Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. • Inhalation: May cause respiratory tract irritation. • Chronic: Prolonged or repeated skin contact may cause defatting and dermatitis. Precaution • Use personal protective equipment. • Avoid dust formation. • Avoid breathing vapours, mist or gas. • Ensure adequate ventilation. • Do not let product enter drains. • Keep in suitable, closed containers for disposal Uses 4'-Methylacetophenone is a methylated acteophenone used in cosmetics and perfumery. The presence of 4'-Methylacetophenone has been shown to accelerate the photopolymerization of Methyl methacrylate.
4-Methylacetophenone, C9H10O, CAS No.122-00-9 ₹ 350 Get Latest Price
