Alvesin 5E Generic. Price Of Alvesin 5e. Uses, Dosage, Side Effects

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• Amino acid (Alvesin 5E) indications
• Amino acid (Alvesin 5E) dosage
• Amino acid (Alvesin 5E) interactions
• Amino acid (Alvesin 5E) side effects
• Amino acid (Alvesin 5E) contraindications

Consists of Amino acid, chaát Г±ieän giaГ»i

What is Amino acid (Alvesin 5E)?

Providing nutrition to the body.

Amino acid (Alvesin 5E) is an Amino acid (Alvesin 5E) to be infused intravenously (IV) (into the vein).

Amino acid (Alvesin 5E) indications

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Amino acid (Alvesin 5E)® (Amino Acid) Injection is indicated as an adjunct in the offsetting of nitrogen loss or in the treatment of negative nitrogen balance in potentially reversible renal decompensation when the alimentary tract cannot or should not be used; gastrointestinal absorption of protein is impaired; or metabolic requirements for protein are substantially increased, as with extensive burns.

How should I use Amino acid (Alvesin 5E)?

Use Amino acid (Alvesin 5E) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Amino acid (Alvesin 5E) is administered as an infusion at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
• Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
• If you miss a dose of Amino acid (Alvesin 5E), contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Amino acid (Alvesin 5E).

Amino acid (Alvesin 5E) dosage

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Amino acid (Alvesin 5E) Dosage

Generic name: amino acid

Dosage form: Injection Pharmacy Bulk Package

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

If a patient is unable to take oral nourishment for a prolonged period of time, institution of total parenteral nutrition (TPN) with exogenous calories should be considered.

Fat emulsion coadministration should be considered when prolonged (more than 5 days) parenteral nutrition is required in order to prevent essential fatty acid deficiency (EFAD). Serum lipids should be monitored for evidence of EFAD in patients maintained on fat free TPN.

Adult:

The total daily dose of Amino acid (Alvesin 5E)® (Amino Acid) Injection depends on the patient's metabolic requirement and clinical response. The determination of nitrogen balance and accurate daily body weights, corrected for fluid balance, are probably the best means of assessing individual nitrogen requirements.

Nutritional management of renal decompensation includes providing sufficient amino acid and caloric support for protein synthesis while not exceeding renal capacity for excretion of metabolic wastes. A dosage of 2.5 to 5.0 grams of nitrogen per day with adequate calories will maintain nitrogen equilibrium in most patients with uremia. If more nitrogen and calories are required, higher dosages may be administered, provided great care is taken to avoid exceeding limits of fluid intake or glucose tolerance.

Dosage should be guided by fluid, glucose and nitrogen tolerances, as well as metabolic and clinical responses. The rate of increase in blood urea nitrogen concentration generally diminishes when infusion of amino acids is accompanied by adequate calories. However, excessive intake of protein or increased protein catabolism may alter this response.

The usual daily dose ranges from 250 to 500 mL of Amino acid (Alvesin 5E)® (Amino Acid) Injection equivalent to 2.5 to 5.0 grams of nitrogen in 16.2 to 32.5 grams of amino acids.

Adequate calories should be administered simultaneously.

Patients receiving Amino acid (Alvesin 5E)® (Amino Acid) Injection should be monitored carefully and their electrolyte requirements individualized. Electrolyte supplementation may be required. This injection contains approximately 60 mEq acetate and 31 mEq chloride.

Electrolyte (phosphorous, potassium and magnesium) concentrations usually fall during administration of Amino acid (Alvesin 5E)® (Amino Acid) Injection. Particular care should be taken in the presence of cardiac arrhythmias or digitalis toxicity to assure that these electrolytes are supplemented when necessary.

Children:

Pediatric requirements vary depending upon growth, nutritional state and degree of renal insufficiency. A dosage of 0.5 to 1.0 gram of amino acids per kilogram body weight per day will meet the requirements of the majority of pediatric patients. Initial daily dosage should be low and increased slowly. More than one gram of essential amino acids per kilogram of body weight per day is not recommended. The total volume of nutritional solution, and the rate at which it is administered, will vary with the child’s age, nutritional and growth state, as well as the degree of renal failure. See Special Precautions in Pediatric Patients for additional information.

Maintenance vitamins, additional electrolytes and trace elements should be administered as required.

Central Vein Administration:

Hypertonic mixtures of amino acids and dextrose may be administered safely by continuous infusion through a central vein catheter with the tip located in the vena cava. In addition to meeting nitrogen needs, the administration rate is governed, especially during the first few days of therapy, by the patient's tolerance to dextrose. Daily intake of amino acids and dextrose should be increased gradually to the maximum required dose as indicated by frequent determinations of urine and blood sugar levels.

Uremic patients frequently are glucose intolerant. Provision of adequate calories in the form of hypertonic dextrose may require the administration of exogenous insulin to prevent hyperglycemia and glycosuria.

Parenteral nutrition may be started at lower administration rates and with infusates containing lower concentrations of dextrose; dextrose content and rate may be gradually increased to estimated caloric needs as the patient’s glucose tolerance increases. The patient’s fluid, nitrogen and glucose tolerance should be the determining factor of the rate of administration.

Sudden cessation in administration of concentrated dextrose solutions may result in insulin reactions due to continued endogenous insulin production. Such solutions should be withdrawn slowly.

Peripheral Vein Administration:

For patients requiring parenteral nutrition in whom the central vein route is not indicated, this injection can be mixed with low concentration dextrose solutions and administered by peripheral vein with fat emulsions.

Intravenous fat emulsions provide approximately 1.1 kcal/mL (10%) or 2.0 kcal/mL (20%) and may be administered along with amino acid-dextrose solutions through a short Y-connector near the infusion site to supplement caloric intake. Fat, however, should not be the sole caloric intake since studies have indicated that glucose is more nitrogen sparing in the stressed patient.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit. Use of a final filter is recommended during administration of all parenteral solutions where possible.

Do not use unless solution is clear and vacuum is present. Unit must be used with a vented set or a nonvented set with a vented spike adapter.

Amino acid (Alvesin 5E)® (Amino Acid) Injection in the Pharmacy Bulk Package is intended for use in the preparation of sterile, intravenous admixtures. Additives may be incompatible with the fluid withdrawn from this container. Complete information is not available. Those additives known to be incompatible should not be used. Consult with pharmacist, if available. When compounding admixtures, use aseptic technique. Mix thoroughly. Do not store any unused portion of Amino acid (Alvesin 5E)® (Amino Acid) Injection.

Solutions should be used promptly after mixing. Any storage should be under refrigeration and limited to a brief period of time, preferably less than 24 hours.

More about Amino acid (Alvesin 5E) (parenteral nutrition solution)

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Professional resources

• Amino acid (Alvesin 5E) (FDA)

Amino acid (Alvesin 5E) interactions

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Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly.

Amino acid (Alvesin 5E) side effects

See also:What are the possible side effects of Amino acid (Alvesin 5E)?

Reactions reported in clinical studies as a result of infusion of the parenteral fluid were water weight gain, edema, increase in BUN, and dilutional hyponatremia. Asterixis was reported to have worsened in one patient during infusion of the Amino acid (Alvesin 5E).

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.

Symptoms may result from an excess or deficit of one or more of the ions present in the solution; therefore, frequent monitoring of electrolyte levels is essential.

Phosphorus deficiency may lead to impaired tissue oxygenation and acute hemolytic anemia. Relative to calcium, excessive phosphorus intake can precipitate hypocalcemia with cramps, tetany and muscular hyperexcitability.

If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures, and save the remainder of the fluid for examination if deemed necessary.

Amino acid (Alvesin 5E) contraindications

See also:What is the most important information I should know about Amino acid (Alvesin 5E)?

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Aminosyn-HF 8% (amino acid injection 8%) is contraindicated in patients with anuria, inborn errors of amino acid metabolism, especially those involving branched chain amino acid metabolism such as Maple Syrup Urine Disease and Isovaleric Acidemia, or hypersensitivity to one or more amino acids present in the solution.

Active ingredient matches for Alvesin 5E:

Amino acid/chaát Г±ieän giaГ»i in Vietnam.

Unit description / dosage (Manufacturer)	Price, USD
Alvesin 5E 10 Bottle 250 mL
Alvesin 5E 10 Bottle 500 mL
List of Alvesin 5E substitutes (brand and generic names):
Amino acid/chaát Г±ieän giaГ»i (Vietnam)

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Information checked by Dr. Sachin Kumar, MD Pharmacology