Anti-HPV18E6 [C1N1] | Monoclonal Antibodies - Ximbio

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Anti-HPV18E6 [C1N1]

Invented by Dr Lawrence Banks from International Centre For Genetic Engineering And Biotechnology (ICGEB)

Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields

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• References (2)
• Inventor Info

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Info

Catalogue Number	152765
Applications	ELISA IP WB
Antigen/Gene or Protein Targets	Human papillomavirus type 18 (HPV-18) specific epitopes on the E6 polypeptide
Synonyms	HPV-18 E6, HPV-18 E6 protein, HPV18 E6, HPV18E6
Reactivity	Virus
Relevance	The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. BF7 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies.
Host	Mouse
Immunogen	HPV18E6-beta-galactosidase fusion protein synthesized in E. coli
Positive Control	HPV infected tissue
Subclass	IgG
Molecular Weight (kDa)	16.5
Myeloma Used	P3/NS1/1-Ag4.1
Strain	Balb/c
Research Area	Cancer, Virology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Banks et al. 1987. J Gen Virol. 68 ( Pt 5):1351-9. PMID: 3033140.

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Identification of human papillomavirus type 18 E6 polypeptide in cells derived from human cervical carcinomas.

Europe PMC ID: 3033140

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References: 2 entries

Banks et al. 1987. J Gen Virol. 68 ( Pt 5):1351-9. PMID: 3033140.

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Identification of human papillomavirus type 18 E6 polypeptide in cells derived from human cervical carcinomas.

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Inventor Information

Inventors

	Dr Lawrence Banks
	from International Centre For Genetic Engineering And Biotechnology (ICGEB) Linked to 5 other reagents on Ximbio.

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Invented at

	Cancer Research UK London Research Institute: Lincoln's Inn Fields
	334 reagents listed on Ximbio

OBTAIN THIS REAGENT

This reagent can be obtained from the following supplier. Click through to their website for more details.

CancerTools.org

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