Basal Ganglia Infarction Associated With HHV-6 Infection - PubMed

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Abstract

A 6 year old boy presented with meningoencephalitis and was found to have serological evidence of acute human herpes virus-6 (HHV-6) infection. He did not develop symptomatic seizures or the rash of exanthum subitum (roseola). His course was marked by severe spastic quadriparesis associated with radiological evidence of basal ganglia infarction. HHV-6 infection should be considered in any child with acute meningoencephalitis.

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• Chronic Alcoholism and HHV-6 Infection Synergistically Promote Neuroinflammatory Microglial Phenotypes in the Substantia Nigra of the Adult Human Brain. Jain N, Smirnovs M, Strojeva S, Murovska M, Skuja S. Jain N, et al. Biomedicines. 2021 Sep 14;9(9):1216. doi: 10.3390/biomedicines9091216. Biomedicines. 2021. PMID: 34572401 Free PMC article.
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• Detection of antibodies directed against human herpesvirus 6 U94/REP in sera of patients affected by multiple sclerosis. Caselli E, Boni M, Bracci A, Rotola A, Cermelli C, Castellazzi M, Di Luca D, Cassai E. Caselli E, et al. J Clin Microbiol. 2002 Nov;40(11):4131-7. doi: 10.1128/JCM.40.11.4131-4137.2002. J Clin Microbiol. 2002. PMID: 12409386 Free PMC article.

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