C3 / C4 Complement Test - Normal Range, Procedure, Results & More

• Our Services

PhysiotherapyNursingMedical EquipmentTrained AttendantsLab TestsElder CareDoctor ConsultationMother & Baby CareDiabetes CareCritical CareCovid CareVaccinationCounsellingNutrition & Diet Consultation
• About Us
• Investor Relations
• Book Now

+1800 121 2323+1800 121 2323(India)+1 (979) 401-2323(outside India)

• Our Services
• About Us
• Investor Relations
• +1800 121 2323
• Book Now

• Home
• Diagnostics
• Lab Tests
• c3 and c4 blood test

c3 and c4 blood testHome PickupNameMobile Number*City*Service Needed In?AhmedabadAsansolBangaloreBhopalBhubaneswarChandigarhChennaiCochinCoimbatoreDelhiDurgapurFaridabadGhaziabadGurgaonGuwahatiHyderabadIndoreJaipurKolkataLucknowMumbaiNagpurNashikNoidaPuneSalemSuratVadodaraVijayawadaVisakhapatnam

*I authorize Portea representative to contact me. I understand that this will override the DND status on my mobile number.

Book Now

Table of Contents

• What is C3?
• What is C4?
• C3 & C4 Blood Test
• When is C3 and C4 Blood Test needed
• C3 and C4 blood test procedure
• C3 Normal Range
• C4 Normal Range
• C3 and C4 blood test side effects
• How can we help?
• References

what is c3?

Complement component 3 more popularly called just C3 is a protein of the immune system. C3 plays a vital role in the activation of the complement system and back the innate immunity. People suffering from C3 deficiency are more prone to bacterial infection.

what is c4?

Complement component 4 popularly called C4 is also a protein that is significantly involved in the intricate complement system. It originates from human leukocyte antigen (HLA) system. C4 performs many crucial functions in the immunity, tolerance and autoimmunity. C4 is also a significant factor in the connection of the recognition pathways of the overall system prompted by the antibody – antigen complexes to the other effector proteins of the innate immune response.

c3 & c4 blood test

C3 & C4 Blood Test measures the levels of Complement component 3 and Complement component 4 in the blood. The complement system comprises of more than 30 proteins in the blood, that play a significant role in the body’s immune system. Assessing the volume of one or more complements can help in ascertaining of any abnormality in the complement system that can result in varied health problems. Of all the complements, C3 and C4 are the ones that are mostly tested.

Low complement levels can expose a person to the risk of infections and autoimmune disorders. Low complement levels are also with several health conditions like;

• Increased bacterial infections
• Rheumatoid Arthritis
• Cirrhosis
• Hepatitis
• Kidney disease
• Malnutrition and
• Septicemia
• High Complement levels are associated with cancer, ulcerative colitis or thyroiditis.

when is c3 and c4 blood test needed

The C3 and C4 blood test is advised if a person is experiencing the following symptoms;

• Extreme Fatigue
• Muscle Pain
• Joint Pain
• Unintended weight loss
• Muscle Weakness
• Muscle Paralysis

c3 and c4 blood test procedure

The C3 and C4 blood test procedure involves a small sample of the patient’s blood drawn out with the help of an injection.

Preparation for C3 and C4 blood test

No specific preparation is required for C3 and C4 test, although you do need to inform your doctor about the medication or supplements you are taking prior to undergoing the test.

c3 normal range

The C3 normal range in males is 88 – 252 mg/dL and the C3 normal range in women is 88 – 206 mg/dl.

c4 normal range

C4 normal range is between 16 to 48 milligrams per decilitre or 0.16 to 0.48 grams per litre. These levels change significantly with age.

c3 and c4 blood test side effects

C3 and C4 blood test side effects are pretty safe to administer and like any other blood tests, side effects if any are very minor one and usually subside within a day. Some of the side effects of C3 and C4 blood test are as follows;

• Soreness and swelling at the puncture site
• Slight dizziness
• Excessive bleeding

how can we help?

C3 and C4 blood test are of one those lab tests that can be easily done at home as it only involves simple blood samples to be collected from the veins of a person by means of an injection. We offer fully certified C3 and C4 blood test conducted by highly trained lab technicians, so you can trust us with your C3 and C4 blood test need and experience truly world class at home healthcare service at home.

Once you connect with us our representative phlebotomist would come to your home at a time and day of your choosing and collect the blood sample while you sit back and relax. We also deliver the C3 and C4 blood test results online for your convenience.

References

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086056/
2. http://www.ucsfbenioffchildrens.org/tests/003539.html
3. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086056/
4. https://medlineplus.gov/ency/article/003539.htm
5. http://www.ucsfhealth.org/tests/003354.html
6. http://www.bioline.org.br/pdf?pr08033
7. https://labtestsonline.org/tests/complement

View More

Diagnostic TestsLab Packages

• ABOUT US> Our Team> Doctor Speak> Press & Media> Annual Return> Careers> Partner With Us> Contact Us> FAQs> Testimonials
• OUR SERVICES> Physiotherapy> Doctor Consultations> Nursing> Medical Equipment> Trained Attendants> Lab Tests> Counselling
• POPULAR SERVICES> Physiotherapy for Back Pain> Physiotherapy for sports> Eldercare for Parents> Injections and IVs> Cholesterol tests> Refer a friend
• CONTACT US

  For Bookings and Service queries:

  Ph: 1800 121 2323 Email: [email protected]

  For Customer Support & Feedback:

  Ph: 1800 121 2323 Email:[email protected]

*I agree to be contacted by Portea over phone and email. I do not have any objection to receiving emails, messages (SMS or any other mode) and calls from Portea. This consent shall supersede any preferences set through Do Not Disturb (DND Register)/ National Customer Preference Register (NCPR).**Including State Govt. Projects

Privacy Policy | Terms and Conditions | Patient Rights & ResponsibilitiesCopyright © 2025 Portea Medical