20 thg 3, 2019 · The C5 convertases initiate the activation of the terminal complement pathway and the formation of the C5b-9 complexes (24). Upon insertion of ... Abstract · Preface · Mechanisms Underlying... · Normal Cells and Even More...
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20 thg 2, 2018 · C5b-9, also known as the terminal complement complex (TCC) or membrane attack complex (MAC), is a multimer derived from five complement ...
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Complement system activation plays an important role in innate and acquired immunity. Activation of complement leads to the formation of C5b-9 terminal ...
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Assembly of C5b-9 on cell membranes results in transmembrane channels and causes cell death. When the number of C5b-9 molecules is limited, nucleated cells ...
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C5b-C9, termed the complement membrane attack complex is responsible for the cytolytic function of complement, a potent mechanism contributing to innate ...
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13 thg 11, 2019 · Soluble C5b-9 As a Prognostic Biomarker for Thrombotic Microangiopathy at the Onset of Graft-Versus-Host Disease ... Blood (2019) 134 ( ...
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Soluble C5b-9 Assay The complement system consists of three initiating pathways – the classical, alternative and lectin – activation of which leads to the ...
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Sublytic C5b-9 attack reduced the expression of the M phase cell cycle proteins, cyclin B and cdc2, accompanied by reduced mitosis (mitotic figures) and ...
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Deposition of the terminal complement proteins (C5b-9) on human endothelial cells can result in cell lysis or nonlytic alterations of cell function ...
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Description. Rabbit polyclonal to C5b-9 ; Host species. Rabbit ; Specificity. This antibody is monospecific for C5b-9 complex in purified form or present in cobra ...
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The terminal complement complexes C5b-7, C5b-8 and C5b-9 are able to generate nonlethal cell signals. One universal consequence of a cell being targeted by ...
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sC5b-9 is the non-cytolytic, soluble form of the terminal complement complex C5b-9 (TCC or membrane attack complex MAC). The quantitative measurement of ...
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The monoclonal antibody 2A1 recognizes rat C5b-9. The antibody was shown to compete with antibodies to human C9 for its binding site on the C5b-9 complex, ...
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The antibody is directed against a neoepitope formed by poly (C9) in the terminal complement complex (TCC). It reacts both with the membrane-bound C5b-9(m) ...
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