Top 15+ Cc-90011 hay nhất
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1.Discovery Of CC-90011: A Potent And Selective Reversible Inhibitor ...
9 Oct 2020 · CC-90011 exhibits potent on-target induction of cellular differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) ... Abstract · Introduciton · Results and Discussion · Experimental Section
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2.Discovery Of CC-90011: A Potent And Selective ... - PubMed
10 Dec 2020 · CC-90011 exhibits potent on-target induction of cellular differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cell ...
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3.A Safety And Efficacy Study Of CC-90011 In Combination With ...
17 Apr 2020 · CC-90011 will be given orally (PO) at a dose of 40 mg on a once weekly basis in a continuous 28-day cycle. Nivolumab will be administered ...
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4.Phase I Study Of CC-90011 In Patients With ... - Annals Of Oncology
Background: CC-90011 is a potent, selective, reversible oral inhibitor of the epigenetic target, lysine-specific demethylase 1A (LSD1) that has demonstrated ...
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5.Phase I Study Of Lysine-Specific Demethylase 1 Inhibitor, CC-90011 ...
CC-90011 is a potent, selective, oral, and reversible inhibitor of LSD1 that decreased growth of various solid tumor cell lines in vitro, including small cell ... Abstract · Patients and Methods · Results · Discussion
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6.Phase 1/2 Study Investigating CC-90011, A Potent, Selective, And ...
5 Nov 2021 · The epigenetic eraser LSD1 demethylates histone lysine residues to alter gene expression, is essential for hematopoiesis, and is often ...
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7.Pulrodemstat (CC-90011) Besylate - LSD1 Inhibitor
Pulrodemstat (CC-90011) besylate (LSD1-IN-7 benzenesulfonate) is a potent and orally active lysine specific demethylase-1 (LSD1) inhibitor that is found to ...
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8.Phase I Study Of CC-90011 In Patients With Advanced Solid Tumors ...
CC-90011 is a selective, reversible inhibitor of the epigenetic target, lysine-specific demethylase 1A (LSD1) that has demonstrated anti-tumor activity against ...
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9.A Phase 1b Study Of CC-90011, A Potent, Reversible, Oral LSD1 ...
50P - A Phase 1b Study of CC-90011, a Potent, Reversible, Oral LSD1 Inhibitor, Plus Etoposide and Cisplatin (EP) or Carboplatin (EC) in Patients (Pts) With ...
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10.Phase I Study Of CC-90011 In Patients With Advanced Solid Tumours ...
CC-90011, a potent, selective, and reversible oral inhibitor of lysine-specific demethylase 1A, has shown antiproliferative activity against cancer cells in ...
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11.Clinical Activity Of CC‐90011, An Oral, Potent, And Reversible LSD1 ...
23 Jun 2022 · CC-90011 is a potent, selective, and reversible oral LSD1 inhibitor that has been shown to increase expression of tumor-suppressing genes and ...
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12.LSD1/KDM1A Inhibitors In Clinical Trials: Advances And Prospects
4 Dec 2019 · ... ORY-1001, GSK-2879552, IMG-7289, INCB059872, CC-90011, and ORY-2001 currently undergo clinical assessment for cancer therapy, ...
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13.CC-90011 | Ligand Page | IUPHAR/BPS Guide To PHARMACOLOGY
Comment: CC-90011 is a clinical stage, selective lysine specific demethylase 1 (LSD1) inhibitor [4]. It is a reversible inhibitor. LSD1 inhibitors have ...
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14.Pulrodemstat Benzenesulfonate (CC-90011 ... - MedChemExpress
Rating 4.5 (1) CC-90011 benzenesulfonate is a potent, selective, reversible and orally active inhibitor of lysine specific demethylase-1 (LSD1) with an IC50 of 0.25 nM.
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15.CC-90011-ST-001 - Health Research Authority
CC-90011 is an experimental drug that inhibits LSD1 (lysine-specific demethylase 1A), a molecule that regulates the function of many genes important in cancer ...
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