Homozygous Ch25h (cholesterol 25-hydroxylase) knock-out mice have increased levels of IgA and may be useful in studies innate and adaptive immune system ...
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27 Mar 2020 · On HFD, Ch25h KO mice became obese but exhibited reduced plasma insulin levels, improved insulin action, and decreased ectopic lipid deposit.
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We found that obese Ch25h KO mice exhibited improved insulin resistance and features of reduced adipose tissue inflammation due to the attenuation of CD11c+ ...
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28 Aug 2020 · Ch25h-knockout mice affects B cell and increases the serum levels of IgA. A lack of Ch25h markedly increases the aggressiveness markedly of ...
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25 Nov 2020 · Cholesterol 25-hydroxylase (CH25H) is an interferon ... CH25H knockout was verified by both Sanger sequencing and Western blot (SI Appendix, ...
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Given that KDO treatment increases CH25H mRNA levels within lymph nodes (Fig. 4A) and that mucosal IgA levels are altered in the 2 lines of knockout mice ...
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6 Jun 2022 · Complete information for CH25H gene (Protein Coding), ... Cyagen: Research-Ready Knockout Catalog Models KO Mouse Strain for CH25H ...
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17 Jun 2020 · CH25H knockout mice [66] were purchased from the Jackson laboratory (JAX stock #016263) and maintained as homozygotes.
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11 Apr 2019 · The enzyme cholesterol 25-hydroxylase [CH25H] converts cholesterol ... Reduced collagen deposition in Ch25h knockout mice was demonstrated ...
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17 May 2021 · Here we characterized cholesterol 25-hydroxylase (CH25H) ... Knockout of endothelial CH25H stimulated angiogenesis and tumor growth in mice.
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8 Dec 2021 · Homozygous Ch25h KO mice (Ch25h KO) backcrossed to C57BL/6J mice for >10 generations (Bauman et al., 2009) were obtained from The Jackson ...
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cholesterol 25-hydroxylase (Ch25h) was strongly upre- gulated by LPS and that injection of LPS into ... Ch25h double knockout mice showed a more severe.
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1 Feb 2022 · PS19 tauopathy mice previously crossed with ApoE targeted replacement (TR) mice were subsequently crossed with CH25H KO mice.
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CH25H CRISPR Knockout and Activation Plasmids (h) designed to edit, knockdown or upregulate human CH25H gene expression.
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