14 Jan 2020 · We found that melanoma TEV downregulated type I interferon (IFN) receptor and expression of IFN-inducible cholesterol 25-hydroxylase (CH25H). SUMMARY · RESULTS · DISCUSSION · METHOD DETAILS
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26 Mar 2013 · Here, we investigated expression and transcriptional regulation of cholesterol 25-hydroxylase (CH25H) in human U87MG and GM133 glioblastoma cell ...
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Expression of CH25H in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers.
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17 May 2021 · Here we characterize endothelial CH25H as a key genetic suppressor of ICBT and of ICBT-driven activation of ECs, as well as of intratumoral ...
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17 May 2021 · Here we characterized cholesterol 25-hydroxylase (CH25H) ... Knockout of endothelial CH25H stimulated angiogenesis and tumor growth in mice.
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Results of this study uncover the key role of CH25H in defense against normal cells' education by tumor-derived ves-.
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6 Jul 2020 · CH25H and 25HC in Regulating Cholesterol Metabolism ... Barber, G.N. STING: Infection, inflammation and cancer. Nat. Rev. Immunol.
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14 Jan 2019 · Tumor-derived extracellular vesicles (TEV) downregulate IFNAR1 and CH25H. •. CH25H acts to restrict TEV uptake and limit the education of ...
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(C) Scatterplot of quantitative stromal CH25H protein expression levels in normal adjacent stroma and tumor stroma (Cohort 1). (D) Kaplan-Meier survival ...
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11 Apr 2019 · The enzyme cholesterol 25-hydroxylase [CH25H] converts cholesterol ... due to adenocarcinoma [non cancer-affected ileal resection margin].
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(C) Growth of MH6499c4 pancreatic ductal adenocarcinoma tumors (inoculated s.c. at 1 × 10 5 cells/mouse) in WT and Ch25h -/-mice. n = 12-13 for each group. (D) ...
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13 Oct 2021 · (24) Upregulation of CH25H has been reported to inhibit the uptake and metastasis of tumor-derived EVs by normal cells.
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View mouse Ch25h Chr19:34451183-34452548 with: phenotypes, sequences, polymorphisms, ... neoplasm. nervous system. pigmentation. renal/urinary system.
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4 Jan 2022 · However, the effect on tumor cells of necrotic debris, ... APOL3, APOA1, and cholesterol-25-hydroxylase (CH25H) displayed a four to ...
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