Cobas C 111 Analyzer - Roche Diagnostics

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For in vitro diagnostic use. Instrument cobas c 111 IVD cobas® c 111 analyzer INS_526 04 528 778 001 4 528 778 001 04528778001 4528778001 04528778001 cobas c 111 analyzer cobas c 111 analyzer 04015630927036 Instruments Not Available Not Available The cobas c 111 analyzer is a continuous randomaccess analyzer intended for the in vitro determination of clinical chemistry parameters in serum, plasma, urine or whole blood (HbA1c).The cobas c 111 analyzer is intended for professional testing.The cobas c 111 analyzer is not intended for nearpatient testing.The analyzer is optimized for a small workload of up to 50 samples per day, utilizing photometric analysis. en Physical DimensionsWidth (with ISE Unit)590mm (720mm)Depth (with ISE Unit)550mm (550mm)Height (with ISE Unit)480mm (480mm)Weight (with ISE Unit)32.5 kg (39.5 kg)ThroughputPhotometric85 tests/h max60 tests/h consolidated(with typical test panel)ISE180 tests/h max60-100 tests/h consolidated(photometric and ISE mixed)SamplesSample handlingManually by operatorTime to first result5 – 10 min(photometric measurements)2 min(ISE measurements)CalibratorsRoche calibratorsSee the package inserts of the reagentsReagent BottlesReagent bottles20mL maximumIdentificationBarcodeBarcode2-D / format PDF417Number of tests50 – 200 tests(depending on the test)Reagent bottles20mL maximumCuvettesSegments of 10 cuvettesManual insertion and removal of segmentsSingle useCuvettes are for single use onlyStatic incubation temperature in cuvette37°C (±0.5°C)PhotometerAbsorbance photometer20W halogen lamp12 wavelengths340 – 659nmSensorPhotosensitive diode array en

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2. cobas® c 111 analyzer

cobas® c 111 analyzer IVD For in vitro diagnostic use.

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Small footprint. Big performance

The cobas® c 111 analyzer is the smallest member of Roche’s cobas® core lab clinical chemistry platform family, delivering reliable results at a throughput of up to 85 tests per hour, with high accuracy and precision.1-6

With a small footprint of only 0.3m², the cobas c 111 analyzer offers over 40 different tests, with the same reagent chemistry as the broader cobas® platform, combining compact convenience with diagnostic versatility.1

Designed for durability, it requires maintenance visits only once every 1.5 years.7 Roche’s proven technology is trusted by laboratories worldwide, with more than 6,700 active installations of the cobas c 111 across 125 countries.8

An instrument designed to fit in many ways

Routine

Perfectly suited as a main analyzer for small labs, small hospitals and clinics, and satellite labs of larger networks.

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Perfectly suited as a main analyzer for small labs, small hospitals and clinics, and satellite labs of larger networks.

Backup

Serves well as a backup analyzer for larger cobas® clinical chemistry analyzers.

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Serves well as a backup analyzer for larger cobas® clinical chemistry analyzers.

Dedicated

Used as a dedicated analyzer for STAT samples in emergency and intensive care departments by trained lab professionals, as well as for specialized testing, such as HbA1c-only analysis.

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Used as a dedicated analyzer for STAT samples in emergency and intensive care departments by trained lab professionals, as well as for specialized testing, such as HbA1c-only analysis.

Close Benefits at a glance

Benefits at a glance

Exchangeable disks for flexible reagent handling 

• Preparation of up to 8 different reagent disks adaptable to individual panel testing
• Each reagent disk can hold up to 27 bottles which allows for 13 different tests in one reagent disk Prepared reagent disks can be stored in a fridge until needed and with one disk on board (within the shelf life of the respective parameter)

Low water consumption of up to 3 liters per day

Independent and flexible water supply with 3 liter water and waste containers.

Intuitive software design for easy operation

• Guiding software wizard for daily start-up and maintenance procedure
• “Time to Result” indicator for predictable walkaway time

Streamlined sample handling for enhanced efficiency

• Easily load any sample tube type into the sample loading area, without the need for manual configuration
• Experience uninterrupted workflow with continuous sample loading (up to 60 cuvettes), eliminating the need to stop the instrument for new samples

Proven consistent results5,6

• Same reagents used for cobas® c packs and cobas® c 111 reagent bottles, delivering comparable results across the cobas platform
• Same calibrators and controls available for all cobas® clinical chemistry analyzers

Related categories

Related Information

• cobas® c 111 analyzer product brochure for core lab
• cobas® c 111 analyzer product brochure for the Point of Care

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Overview

Ordering information

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Product specification	Value
Physical dimensions	Width: 590 mm Depth: 550 mm Height: 480 mm Weight: 32 kg
Test throughput	Photometric: 85 tests/h max 60 tests/h consolidated (with typical test panel) ISE: 180 tests/h max 60-100 tests/h consolidated (photometric and ISE mixed)
Time to first result	Photometric: 5 – 10 min ISE: 2 min
Sample types	Serum, plasma, urine, whole blood (HbA1c)
Sample input	Continuous loading of primary and secondary tubes into 8 sample positions Priority STAT sampling

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Technical documents

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References

1. F. Hoffmann-La Roche Ltd. cobas® c 111 analyzer User Guide Version 4.5 Software Version 4.3 or higher. (v1). 2023.
2. F. Hoffmann-La Roche Ltd. cobas® c 311 analyzer Operator's Manual Version 3.2 Software Version 01-13. (v3.1). 2023.
3. F. Hoffmann-La Roche Ltd. cobas® pure integrated solutions User Guide Software Version 01-05. (v2.3). 2024.
4. F. Hoffmann-La Roche Ltd. cobas® pro integrated solutions User Guide Software Version 03-02. (v4.1). 2025.
5. F. Hoffmann-La Roche Ltd. Calculated method comparison of cobas c 501 vs. cobas c 111. Data on file. 2023.
6. F. Hoffmann-La Roche Ltd. Measured method comparison of cobas c 503 vs. cobas c 111. Data on file. 2023.
7. F. Hoffmann-La Roche Ltd. GCS Product Report for Instruments, Executive Summary. Data on file. 2023.
8. F. Hoffmann-La Roche Ltd. ICB Instrument Dashboard - Number of countries and installations. Data on file. 2024.

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