Complete Blood Count (CBC) - Mayo Clinic

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Overview

A complete blood count (CBC) is a blood test. It's used to look at overall health and find a wide range of conditions, including anemia, infection and leukemia.

A complete blood count test measures the following:

Red blood cells, which carry oxygen
White blood cells, which fight infection
Hemoglobin, the oxygen-carrying protein in red blood cells
Hematocrit, the amount of red blood cells in the blood
Platelets, which help blood to clot

A complete blood count can show unusual increases or decreases in cell counts. Those changes might point to a medical condition that calls for more testing.

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Why it's done

A complete blood count is a common blood test done for many reasons:

To look at overall health. A complete blood count can be part of a medical exam to check general health and to look for conditions, such as anemia or leukemia.
To diagnose a medical condition. A complete blood count can help find the cause of symptoms such as weakness, fatigue and fever. It also can help find the cause of swelling and pain, bruising, or bleeding.
To check on a medical condition. A complete blood count can help keep an eye on conditions that affect blood cell counts.
To check on medical treatment. A complete blood count may be used to keep an eye on treatment with medicines that affect blood cell counts and radiation.

More Information

Anemia
Anorexia nervosa
Antisocial personality disorder
Ataxia
Breast cancer
Burning mouth syndrome
Chronic lymphocytic leukemia
Chronic myelogenous leukemia
Colon cancer
Cyclothymia (cyclothymic disorder)
Dementia
Depression (major depressive disorder)
Enlarged spleen (splenomegaly)
Fibromyalgia
Gilbert syndrome
Hairy cell leukemia
Heart disease
High blood pressure in children
Illness anxiety disorder
Immune thrombocytopenia (ITP)
Kawasaki disease
Lupus
Median arcuate ligament syndrome (MALS)
Multiple myeloma
Myelodysplastic syndromes
Myelofibrosis
Personality disorders
Polycythemia vera
Porphyria
Post-vasectomy pain syndrome
Sexually transmitted diseases (STDs)
Swollen lymph nodes
Tetralogy of Fallot
Thalassemia
Thrombocytosis
Tonsillitis
Uterine fibroids
Vitiligo

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How you prepare

If your blood sample is being tested only for a complete blood count, you can eat and drink as usual before the test. If your blood sample also will be used for other tests, you might need to fast for a certain amount of time before the test. Ask your health care provider what you need to do.

What you can expect

For a complete blood count, a member of the health care team takes a sample of blood by putting a needle into a vein in your arm, usually at the bend in your elbow. The blood sample is sent to a lab. After the test, you can return to your usual activities right away.

Results

The following are expected complete blood count results for adults. The blood is measured in cells per liter (cells/L) or grams per deciliter (grams/dL).

Red blood cell count	Male: 4.35 trillion to 5.65 trillion cells/L Female: 3.92 trillion to 5.13 trillion cells/L
Hemoglobin	Male: 13.2 to 16.6 grams/dL (132 to 166 grams/L) Female: 11.6 to 15 grams/dL (116 to 150 grams/L)
Hematocrit	Male: 38.3% to 48.6% Female: 35.5% to 44.9%
White blood cell count	3.4 billion to 9.6 billion cells/L
Platelet count	Male: 135 billion to 317 billion/L Female: 157 billion to 371 billion/L

Not a definitive test

A complete blood count, also called a CBC, usually doesn't give all the answers about a diagnosis. Results outside the expected range may or may not need follow-up. A health care provider might need to look at the results of other tests as well as the results of a CBC.

For example, results slightly outside the typical range on a CBC might not be of concern for someone who's healthy and has no symptoms of illness. Follow-up might not be needed. But for someone having cancer treatment, the results of a CBC outside the expected range might signal a need to change the treatment.

In some cases, for results that are way above or below the expected ranges, a health care provider might ask you to see a doctor who treats blood disorders, called a hematologist.

What the results may indicate

Results in the following areas above or below the typical ranges on a complete blood count might point to a problem.

Red blood cell count, hemoglobin and hematocrit. The results of these three are related because they each measure a feature of red blood cells.

Lower than usual measures in these three areas are a sign of anemia. Anemia has many causes. They include low levels of certain vitamins or iron, blood loss, or another medical condition. People with anemia might feel weak or tired. These symptoms may be due to the anemia itself or the cause of anemia.

A red blood cell count that's higher than usual is known as erythrocytosis. A high red blood cell count or high hemoglobin or hematocrit levels could point to a medical condition such as blood cancer or heart disease.
White blood cell count. A low white blood cell count is known as leukopenia. A medical condition such as an autoimmune disorder that destroys white blood cells, bone marrow problems or cancer might be the cause. Certain medicines also can cause a drop in white blood cell counts.

A white blood cell count that's higher than usual most commonly is due to an infection or inflammation. Or it could point to an immune system disorder or a bone marrow disease. A high white blood cell count also can be a reaction to medicines or hard exercise.
Platelet count. A platelet count that's lower than usual is known as thrombocytopenia. If it's higher than usual, it's known as thrombocytosis. Either can be a sign of a medical condition or a side effect from medicine. A platelet count that's outside the typical range will likely lead to more tests to diagnose the cause.

Your health care provider can tell you what your complete blood count results mean.

By Mayo Clinic Staff Request an appointment Doctors & Departments Jan. 14, 2023 PrintShow references

Butte MJ. Laboratory evaluation of the immune system. https://www.uptodate.com/contents search. Accessed Oct. 20, 2022.
CBC with differential, blood. Mayo Medical Laboratories. http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/9109. Accessed Oct. 20, 2022.
Understanding blood counts. Leukemia and Lymphoma Society. https://www.lls.org/treatment/lab-and-imaging-tests/understanding-blood-counts. Accessed Oct. 20, 2022.
Understanding your complete blood count (CBC) tests. American Society of Clinical Oncology. https://www.cancer.net/navigating-cancer-care/diagnosing-cancer/reports-and-results/understanding-your-complete-blood-count-cbc-tests. Accessed Oct. 20, 2022.
Hoffman R, et al. Resources for the hematologist: Interpretive comments and selective reference values for neonatal, pediatric and adult populations. In: Hematology: Basic Principles and Practice. 7th ed. Elsevier; 2018. https://www.clinicalkey.com. Accessed Oct. 20, 2022.

Anemia
Anorexia nervosa
Antisocial personality disorder
Ataxia
Blood Basics
Breast cancer
Burning mouth syndrome
Cancer
Chronic lymphocytic leukemia
Chronic myelogenous leukemia
Colon cancer
Cyclothymia (cyclothymic disorder)
Dementia
Depression (major depressive disorder)
Enlarged spleen (splenomegaly)
Fibromyalgia
Gilbert syndrome
Hairy cell leukemia
Heart disease
High blood pressure in children
Illness anxiety disorder
Immune thrombocytopenia (ITP)
Kawasaki disease
Lupus
Median arcuate ligament syndrome (MALS)
Microcephaly
Monoclonal gammopathy of undetermined significance (MGUS)
Multiple myeloma
Myelodysplastic syndromes
Myelofibrosis
Personality disorders
Polycythemia vera
Porphyria
Post-vasectomy pain syndrome
Sexually transmitted diseases (STDs)
Swollen lymph nodes
Tetralogy of Fallot
Thalassemia
Thrombocytosis
Tonsillitis
Uterine fibroids
Vitiligo

Show more related content

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A Book: Mayo Clinic Family Health Book
Newsletter: Mayo Clinic Health Letter — Digital Edition

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