H157 Cell Line - Ximbio

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H157 Cell Line

Invented at University Of Bristol

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• References (8)
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Info

Catalogue Number	153420
Antigen/Gene or Protein Targets	Human oral squamous cell carcinoma
Tissue	Buccal mucosa
Disease Keywords	Cancer
Model	Tumour line
Relevance	Established from a squamous cell carcinoma (SCC) of the buccal mucosa (20mm-40mm) of a male patient, age 84. STNMP stage II, well differentiated, node positive tumour. Mutant p53, codon 306 exon 8, G to A; wild type K-, N- and Ha-ras. Non-tumourigenic in athymic nude mice by subcutaneous injection and on injection into the floor of the mouth (orthotopic), but form epidermoid cysts subcutaneously
Research Area	Cancer
Growth/Phenotype Keywords	Adherent
Recommended Growing Conditions	Split sub-confluent cultures (70-80%) 1:8 to 1:10 5% CO2; 37°C. Suggested seeding density 5 x 1000 cells/cm². DMEM:HAMS F12 (1:1) + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.5 ug/ml sodium hydrocortisone succinate.
Cellosaurus ID	CVCL_2458

References

There are 8 reference entries for this reagent.

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References: 8 entries

Yeudall et al. 1995. Eur J Cancer B Oral Oncol. 31B(2):136-43. PMID: 7633286.

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Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes expressing mutant p53.

Europe PMC ID: 7633286

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Prime et al. 1994. Br J Cancer. 69(1):8-15. PMID: 8286215.

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Epidermal growth factor and transforming growth factor alpha characteristics of human oral carcinoma cell lines.

Europe PMC ID: 8286215

View

Yeudall et al. 1993. Eur J Cancer B Oral Oncol. 29B(1):63-7. PMID: 8180579.

View

Ras gene point mutation is a rare event in premalignant tissues and malignant cells and tissues from oral mucosal lesions.

Europe PMC ID: 8180579

View

Prime et al. 1990. J Pathol. 160(3):259-69. PMID: 1692339.

View

The behaviour of human oral squamous cell carcinoma in cell culture.

Europe PMC ID: 1692339

View Add a reference

References: 8 entries

Yeudall et al. 1995. Eur J Cancer B Oral Oncol. 31B(2):136-43. PMID: 7633286.

View

Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes expressing mutant p53.

View

Prime et al. 1994. Br J Cancer. 69(1):8-15. PMID: 8286215.

View

Epidermal growth factor and transforming growth factor alpha characteristics of human oral carcinoma cell lines.

View

Yeudall et al. 1993. Eur J Cancer B Oral Oncol. 29B(1):63-7. PMID: 8180579.

View

Ras gene point mutation is a rare event in premalignant tissues and malignant cells and tissues from oral mucosal lesions.

View

Prime et al. 1990. J Pathol. 160(3):259-69. PMID: 1692339.

View

The behaviour of human oral squamous cell carcinoma in cell culture.

View Add a reference

Inventor Information

No inventors are currently linked to this reagent. Add an inventor

Invented at

	University Of Bristol
	16 reagents listed on Ximbio

OBTAIN THIS REAGENT

This reagent can be obtained from the following supplier. Click through to their website for more details.

CancerTools.org

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