Giant cell tumor of bone (GCTB) is a locally aggressive subarticular tumor. Having recently reported that H3.3 G34W mutations are characteristic of this ...
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Therefore, H3.3 G34W/R/V mutant-specific antibodies are useful surrogate markers for the H3F3A genotype and helpful for the diagnosis of GCTB and its variants.
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18 thg 10, 2017 · Primary cell lines with H3.3 G34W showed increased colony formation, infiltration and proliferation, known hallmarks of tumor development.
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H3.3 G34W promotes in neoplastic stromal cells an osteoblast-like progenitor state that enables undue interactions with the tumor microenvironment, driving GCT ...
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Giant cell tumor of bone (GCTB) is a locally aggressive subarticular tumor. Having recently reported that H3.3 G34W mutations are characteristic of this tumor ...
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Expression of H3.3 G34W Distinguishes Giant Cell Tumor of Bone From Its Major Giant Cell-containing Bone and Soft Tissue Mimics, in Particular Aneurysmal Bone ...
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The G34 class of oncohistones occur exclusively in the histone variant H3.3 and are found in 92% of giant cell tumors of the bone (GCTB; G34W/L), 17% of high- ...
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3 . Immunogen, A peptide corresponding to Histone H3.3 G34W mutant. Application, Western Blot ELISA Immunohistochemistry Chromatin IP.
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H3.3 G34W oncohistone mutant Recombinant Rabbit Monoclonal Antibody (4H32L4), ChIP-Verified ; Contains. 0.09% sodium azide ; Storage conditions. Store at 4°C ...
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Invitrogen Anti-H3.3 G34W oncohistone mutant Recombinant Polyclonal (4HCLC), Catalog # 712828. Tested in Western Blot (WB) and ChIP assay (ChIP) ...
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Histone 3.3 G34W (H3F3A G34W) Immunostain, Technical Component Only ... abbreviated version of the Published Name for a test. Histone H3 G34W IHC, Tech Only ...
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H3.3 G34W, G34R and G34V were negative in 121/122 cases of non-GCTB, including chondroblastoma, osteosarcoma, primary aneurysmal bone cyst and other giant cell– ...
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ICC/IF: 293T cells transfected with Histone H3.3 G34W-Myc plasmid. General notes. This product is a recombinant monoclonal antibody, which offers several ...
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Abstract. The neoplastic stromal cells of giant cell tumor of bone (GCTB) carry a mutation in H3F3A, leading to a mutant histone variant, H3.3-G34W, ...
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Buy rabbit monoclonal (RM263) antibody to Histone H3.3 (G34W mutant) (A121292). Applications: WB, IHC and more. Reactivity: Human. ✔️ FREE Shipping.
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