Top 15+ H3.3 K27m hay nhất
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1.K27M Mutation In Histone H3.3 Defines Clinically And Biologically ...
K27M-H3.3 mutation defines clinically and biologically distinct subgroups and is prevalent in DIPG, which will impact future therapeutic trial design. K27M- and ...
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2.H3.3 K27M Depletion Increases Differentiation And Extends Latency ...
15 thg 2, 2019 · Histone H3 K27M mutation is the defining molecular feature of the devastating pediatric brain tumor, diffuse intrinsic pontine glioma (DIPG) ... Abstract · INTRODUCTION · Materials and Methods · Supplementary Material
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3.Reciprocal H3.3 Gene Editing Identifies K27M And G34R ... - Nature
9 thg 7, 2020 · 3K27M and G34R mutations into previously H3.3-wildtype brain cells, while in parallel reverting the mutations in glioma cells back to wildtype.
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4.Histone H3.3 K27M Chromatin Functions Implicate A Network Of ...
19 thg 5, 2022 · The histone variant H3.3 K27M mutation is a defining characteristic of diffuse intrinsic pontine glioma (DIPG)/diffuse midline glioma (DMG).
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5.Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma ...
14 thg 1, 2019 · 3 K27M alone enhanced neural stem cell self-renewal. Neonatal induction of H3.3 K27M cooperated with active PDGFRα mutant and p53 inactivation ...
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6.Article H3.3-K27M Drives Neural Stem Cell-specific Gliomagenesis In ...
8 thg 3, 2021 · H3.3-K27M upregulated bivalent promoter-associated developmental genes, producing diverse outcomes in different cell types. While being fatal ...
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7.The H3.3K27M Oncohistone Affects Replication Stress Outcome And ...
9 thg 11, 2021 · 3K27M affects the response to replication stress. We found that H3.3K27M increases sensitivity to replication stress, leading to mitotic ... Author summary · Results · Discussion · Materials and methods
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8.SF7761 Human DIPG H3.3-K27M Cell Line | SCC126
SF7761 Human DIPG H3.3-K27M Cell Line SF7761 pediatric diffuse intrinsic pontine glioma (DIPG) cell line harbors the histone H3.3 Lys 27-to-methionine ...
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9.Histone Deposition Pathways Determine The Chromatin Landscapes Of ...
9 thg 9, 2020 · Lysine 27-to-methionine (K27M) mutations in the H3.1 or H3.3 histone genes are characteristic of pediatric diffuse midline gliomas (DMGs).
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10.[PDF] H3.3K27M Mutation Controls Cell Growth And Resistance To ... - MDPI
5 thg 11, 2021 · 3K27M mutated histone in three initially H3K27-unmutated pediatric glioma cell lines, Res259, SF188, and KNS42. First, we validated these new H3 ...
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11.Histone H3.3 K27M And K36M Mutations De-repress Transposable ...
4 thg 11, 2021 · 3K27M and its redistribution in H3.3K36M result in transcriptional deregulation of PRC2-targeted eye development and of. piRNA biogenesis genes, ...
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12.The Histone H3.3 K27M Mutation Found In Diffuse Midline Gliomas ...
28 thg 5, 2022 · Figure 1. H3.3K27M mutation alters Ser31 phosphorylation and chromosome segregation. A. Distribution of H3.3 Ser31 phosphorylation during ...
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13.H3.3 K27M Oncohistone Mutant Antibody, ChIP-Verified (MA5-27916)
Invitrogen Anti-H3.3 K27M oncohistone mutant Recombinant Monoclonal (RM192), Catalog # MA5-27916. Tested in Western Blot (WB), Immunohistochemistry (IHC), ...
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14.Diffuse Midline Gliomas With Histone H3 K27M Mutation In Adu...
3 mutation in adult than in pediatric H3 K27M-mt DMGs. TERT promoter mutations and O 6-methylguanine DNA methyltransferase promoter methylation were not ...
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15.K27M Mutation In Histone H3.3 Defines Clinically And ... - SpringerLink
3 thg 6, 2012 · 3 have location-based incidence (brainstem/cortex) and potentially play distinct roles in pediatric GBM pathogenesis. K27M-H3.3 is universally ...
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