Haematology Reference Ranges

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Haematology reference ranges

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• Full blood count
• Coagulation
• Haematinics
• Acute Phase Response Tests
• Haemoglobinopathies

Full blood count

Test	Criteria	Reference range	Units
Haemoglobin	Adult male	130 - 180	g/L
Adult female	115 - 165	g/L
Total White Cell Count	Adult	3.6 - 11.0	x10^9/L
Differential count:
Neutrophils	Adult	1.8 - 7.5	x10^9/L
Lymphocytes	Adult	1.0 - 4.0	x10^9/L
Monocytes	Adult	0.2 - 0.8	x10^9/L
Eosinophils	Adult	0.1 - 0.4	x10^9/L
Basophils	Adult	0.02 - 0.10	x10^9/L
Platelet count	Adult	140 - 400	x10^9/L
Red cell count	Adult male	4.50 - 6.50	x10^12/L
Adult female	3.80 - 5.80	x10^12/L
Haematocrit	Adult male	0.40 - 0.54	L/L
Adult female	0.37 - 0.47	L/L
Mean Cell Volume (MCV)	Adult	80 - 100	fL
Mean Cell Haemoglobin (MCH)	Adult	27 - 32	pg
Reticulocyte Count	Adult / children	0.5 - 2.0	%
Full term infant	2.0 - 6.0	%

Coagulation

Test	Criteria	Reference range	Units
Prothrombin Time (PT)	Adult	9 - 13	s
Activated Partial Thromboplastin Time (APTT)	Adult	22 - 36	s
Fibrinogen	Adult	1.50 - 4.50	g/L
APTT ratio (on Heparin)	Adult	1.5 - 2.5
D-Dimer for DVT	Adult	<500 = Negative>500 = Positive	ng/mlng/ml
D-Dimer for PEConsider following Trust guidance on age related D-Dimers	Patient aged <50Patient aged >50	>500 = Positive>(Age x 10) = Positive	ng/mlng/ml
DRVVT	Adult	30 - 50	s
0.8 - 1.2	ratio
Protein S (Total)	Adult	62 - 156	%
Protein S (Free)	Adult male	72 - 123	%
Adult female	55 - 124	%
Protein C Activity	Adult	70 - 140	%
Antithrombin	Adult	83 - 128	%
Factor II	Adult	50 - 150	%
Factor V	Adult	50 - 150	%
Factor VII	Adult	50 - 129	%
Factor VIII	Adult	50 - 150	%
Factor IX	Adult	65 - 150	%
Factor X	Adult	50 - 150	%
Factor XI	Adult	65 - 150	%
Factor XII	Adult	50 - 150	%
Factor XIII	Adult	0.7 - 1.4	iu/ml

Coagulation normal ranges for neonates are based on gestational age and postnatal age. See reference ranges.

Haematinics

Test	Criteria	Reference range	Units
Ferritin	Adult male	24 - 340	ug/L
Adult female	11 - 310	ug/L
Vitamin B12	Adult	180 - 914	ng/L
Folate	Adult	> 4.0	ug/L

Acute Phase Response Tests

Test	Criteria	Reference range	Units
Plasma Viscosity	Adult	1.50 - 1.72	mPA.s
0 - 3 years	1.25 - 1.47	mPA.s
Erythrocyte Sedimentation Rate (ESR)	Male (0 - 50 years)	1 - 7	mm/h
Male (50+ years)	2 - 10	mm/h
Female (0 - 50 years)	3 - 9	mm/h
Female (50+ years)	5 - 15	mm/h

Haemoglobinopathies

Test	Criteria	Reference range	Units
HbA2	Adult	1.8 - 3.5	%
HbF	Adult	0.0 - 2.0	%

Information:

Updated: October 2025

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