HN1 (gene) - Wikipedia

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  • 1 Nomenclature
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  • 3 References
  • 4 Further reading
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Appearance move to sidebar hide From Wikipedia, the free encyclopedia (Redirected from HN1 (gene)) Protein-coding gene in the species Homo sapiens
JPT1
Identifiers
AliasesJPT1, ARM2, HN1A, HN1, hematological and neurological expressed 1, Jupiter microtubule associated homolog 1
External IDsMGI: 1096361; HomoloGene: 7364; GeneCards: JPT1; OMA:JPT1 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)Genomic location for JPT1Genomic location for JPT1
Band17q25.1Start75,135,248 bp[1]
End75,168,281 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)Genomic location for JPT1Genomic location for JPT1
Band11 E2|11 80.84 cMStart115,388,179 bp[2]
End115,405,213 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • left testis
  • ganglionic eminence
  • right testis
  • ventricular zone
  • mucosa of transverse colon
  • blood
  • cerebellar hemisphere
  • granulocyte
  • gonad
  • rectum
Top expressed in
  • barrel cortex
  • Rostral migratory stream
  • medial ganglionic eminence
  • internal carotid artery
  • external carotid artery
  • fossa
  • condyle
  • superior cervical ganglion
  • neural tube
  • maxillary prominence
More reference expression data
BioGPS
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

51155

15374

Ensembl

ENSG00000189159

ENSMUSG00000020737

UniProt

Q9UK76

P97825

RefSeq (mRNA)
NM_001002032NM_001002033NM_001288609NM_001288610NM_001288611

NM_016185

NM_008258

RefSeq (protein)
NP_001002032NP_001002033NP_001275538NP_001275539NP_001275540

NP_057269

NP_032284

Location (UCSC)Chr 17: 75.14 – 75.17 MbChr 11: 115.39 – 115.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Jupiter microtubule associated homolog 1 is a protein that in humans is encoded by the JPT1 gene.[5][6]

Nomenclature

[edit]

Jupiter is a Drosophila gene.[7]

NOTE: HN1 can also refer to the Notch 1 gene.

See also

[edit]
  • Homolog
  • JPT2
  • Microtubule

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000189159 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020737 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhou G, Wang J, Zhang Y, Zhong C, Ni J, Wang L, Guo J, Zhang K, Yu L, Zhao S (Apr 2004). "Cloning, expression and subcellular localization of HN1 and HN1L genes, as well as characterization of their orthologs, defining an evolutionarily conserved gene family". Gene. 331: 115–23. doi:10.1016/j.gene.2004.02.025. PMID 15094197.
  6. ^ "Entrez Gene: HN1 hematological and neurological expressed 1".
  7. ^ "Jupiter [ Drosophila melanogaster (fruit fly) ]". National Center for Biotechnology Information. 11 Sep 2024.

Further reading

[edit]
  • Laughlin KM, Luo D, Liu C, Shaw G, Warrington KH Jr, Law BK, Harrison JK (2009). "Hematopoietic- and neurologic-expressed sequence 1 (Hn1) depletion in B16.F10 melanoma cells promotes a differentiated phenotype that includes increased melanogenesis and cell cycle arrest". Differentiation. 78 (1): 35–44. doi:10.1016/j.diff.2009.04.001. PMC 2867035. PMID 19427096.
  • Laughlin KM, Luo D, Liu C, Shaw G, Warrington KH Jr, Qiu J, Yachnis AT, Harrison JK (2009). "Hematopoietic- and Neurologic-Expressed Sequence 1 Expression in the Murine GL261 and High-Grade Human Gliomas". Pathol Oncol Res. 15 (3): 437–44. doi:10.1007/s12253-008-9147-4. PMC 2819207. PMID 19145478.
  • Zujovic V, Luo D, Baker HV, Lopez MC, Miller KR, Streit WJ, Harrison JK (2005). "The facial motor nucleus transcriptional program in response to peripheral nerve injury identifies Hn1 as a regeneration-associated gene". J Neurosci Res. 82 (5): 581–91. doi:10.1002/jnr.20676. PMID 16267826. S2CID 5545114.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
  • Zougman A, Wiśniewski JR (2006). "Beyond linker histones and high mobility group proteins: global profiling of perchloric acid soluble proteins". J. Proteome Res. 5 (4): 925–34. doi:10.1021/pr050415p. PMID 16602700.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Li D, Gonzalez O, Bachinski LL, Roberts R (2001). "Human protein tyrosine phosphatase-like gene: expression profile, genomic structure, and mutation analysis in families with ARVD". Gene. 256 (1–2): 237–43. doi:10.1016/S0378-1119(00)00347-4. PMID 11054553.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
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