 | DRUG: Ephedrine hydrochloride | Help |
| Entry | |
|---|
| Name | Ephedrine hydrochloride (JP18/USP);Ephedrine hydrochloride (TN) |
|---|
| Product | REZIPRES (Dr. Reddy's Laboratories) |
|---|
| Formula | C10H15NO. HCl |
|---|
| Exact mass | 201.0920 |
|---|
| Mol weight | 201.69 |
|---|
| Structure |  Mol fileKCF fileDB search |
|---|
| Simcomp | Neighbor |
|---|
| Class | Cardiovascular agent DG01703 Cardiotonic DG01702 Phenethylamine cardiotonic DG01456 Adrenergic receptor agonist Unclassified DG03282 Ephedrine-containing preparation |
|---|
| Remark | | Therapeutic category: | 2118 2221 |
| ATC code: | C01CA26 R01AA03 R01AB05 R03CA02 S01FB02 |
| Chemical structure group: | DG00227 |
| Product (DG00227): | D01386<JP/US> D04018<US> |
| Product (mixture): | D04338<JP> |
|
|---|
| Efficacy | Antitussive, Bronchodilator, Adrenergic receptor agonist |
|---|
| Comment | Phenethylamine derivative |
|---|
| Target | ADRA1 [HSA:148 147 146] [KO:K04135 K04136 K04137]ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]ADRB [HSA:153 154 155] [KO:K04141 K04142 K04143] |
|---|
| Pathway | | hsa04020 | Calcium signaling pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
| hsa04970 | Salivary secretion |
|
|---|
| Interaction | DDI search |
|---|
| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] C CARDIOVASCULAR SYSTEM C01 CARDIAC THERAPY C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES C01CA Adrenergic and dopaminergic agents C01CA26 Ephedrine D01386 Ephedrine hydrochloride (JP18/USP) <JP/US> R RESPIRATORY SYSTEM R01 NASAL PREPARATIONS R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE R01AA Sympathomimetics, plain R01AA03 Ephedrine D01386 Ephedrine hydrochloride (JP18/USP) <JP/US> R01AB Sympathomimetics, combinations excl. corticosteroids R01AB05 Ephedrine D01386 Ephedrine hydrochloride (JP18/USP) <JP/US> R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES R03C ADRENERGICS FOR SYSTEMIC USE R03CA Alpha- and beta-adrenoreceptor agonists R03CA02 Ephedrine D01386 Ephedrine hydrochloride (JP18/USP) <JP/US> S SENSORY ORGANS S01 OPHTHALMOLOGICALS S01F MYDRIATICS AND CYCLOPLEGICS S01FB Sympathomimetics excl. antiglaucoma preparations S01FB02 Ephedrine D01386 Ephedrine hydrochloride (JP18/USP) <JP/US> Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 21 Cardiovascular agents 211 Cardiotonics 2118 Alkaloids D01386 Ephedrine hydrochloride (JP18/USP) 22 Respiratory organ agents 222 Antitussives 2221 Ephedrines and Ephedra herbs D01386 Ephedrine hydrochloride (JP18/USP) Risk category of Japanese OTC drugs [BR:br08312] Second-class OTC drugs Inorganic and organic chemicals Ephedrine D01386 Ephedrine hydrochloride (JP18/USP) Drug groups [BR:br08330] Cardiovascular agent DG01703 Cardiotonic DG01702 Phenethylamine cardiotonic DG00227 Ephedrine D01386 Ephedrine hydrochloride DG01456 Adrenergic receptor agonist DG00227 Ephedrine D01386 Ephedrine hydrochloride Unclassified DG03282 Ephedrine-containing preparation DG00227 Ephedrine D01386 Ephedrine hydrochloride Target-based classification of drugs [BR:br08310] G Protein-coupled receptors Rhodopsin family Adrenaline ADRA1 D01386 Ephedrine hydrochloride (JP18/USP) <JP/US> ADRA2 D01386 Ephedrine hydrochloride (JP18/USP) <JP/US> ADRB D01386 Ephedrine hydrochloride (JP18/USP) <JP/US> Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D01386 Ephedrine hydrochloride D01386 Ephedrine hydrochloride tablets D01386 10% Ephedrine hydrochloride powder D01386 Ephedrine hydrochloride injection Rx-to-OTC switch list in the USA [br08315.html] D01386 Drug groups [BR:br08330] Cardiovascular agent DG01703 Cardiotonic DG01702 Phenethylamine cardiotonic DG00227 Ephedrine DG01456 Adrenergic receptor agonist DG00227 Ephedrine Unclassified DG03282 Ephedrine-containing preparation DG00227 Ephedrine BRITE hierarchy |
|---|
| Other DBs | |
|---|
| KCF data | ShowATOM 13 1 C8x C 17.0325 -17.0009 2 C8x C 17.0325 -18.4031 3 C8x C 18.2497 -19.1041 4 C8x C 19.4598 -18.4031 5 C8y C 19.4598 -17.0009 6 C8x C 18.2497 -16.2999 7 C1c C 20.6653 -16.2999 8 C1c C 21.8762 -16.9938 9 N1b N 23.0872 -16.2927 10 C1a C 24.2981 -16.9867 11 O1a O 20.6609 -14.8977 12 C1a C 21.8793 -18.3959 13 X Cl 29.1200 -17.5000 BOND 12 1 6 1 1 2 5 7 1 3 1 2 2 4 7 8 1 5 2 3 1 6 8 9 1 7 3 4 2 8 9 10 1 9 4 5 1 10 7 11 1 #Up 11 5 6 2 12 8 12 1 #Up |
|---|
| » Japanese version » Back | All links Ontology (7) KEGG BRITE (7) Drug (3) KEGG DGROUP (1) LigandBox (1) SIDER (1) Chemical substance (3) PubChem (1) ChEBI (1) NIKKAJI (1) Gene (18) KEGG ORTHOLOGY (9) KEGG GENES (9) All databases (31) Download RDF |
DBGET integrated database retrieval system