Laboratory Determination Of Vitamin K2 (Menaquinone 7) - Analytice

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Laboratory determination of Vitamin K2 (Menaquinone 7)

Vitamin K (or menaquinone 7, CAS: 2124-57-4), definition and usefulness:

Vitamin K (or menaquinone 7, CAS: 2124-57-4) is an essential nutrient for the body. This vitamin has the particularity of being soluble in fats and exists in two main forms: vitamin K1 and vitamin K2.

Vitamin K1, also known as phylloquinone or phytomedianone, is found mainly in green vegetables and vegetable oils. It is particularly involved in blood clotting.

Vitamin K2 (or menaquinone 7, CAS: 2124-57-4) is found in foods of animal origin and fermented foods. To a lesser extent, it is also synthesized in the body by the intestinal flora. Vitamin K2 participates in bone mineralization and helps prevent heart disease. Vitamin K2 food supplements are mainly available in the form of MK-4 and MK-7.

The level of toxicity of vitamins K1 and K2 is very low, even at high doses. The decree of 9 May 2006 confirms that vitamin K is one of the nutrients that can be used in the manufacture of food supplements.

Laboratory analysis of vitamin K2 (or menaquinone 7, CAS: 2124-57-4):

Analytice proposes the quantification of vitamin K2 as well as vitamin K1 in foods and food supplements through a laboratory specialized in vitamin analysis or a laboratory with ISO 17025 accreditation recognized by COFRAC (ILAC full member).

Example of vitamin K2 dosage in a laboratory: Analytical technique: LC-FLUO or HPLC-DAD Method: internal LQ: according to the matrix

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Internal reference “vitamin K2” :  12212|

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