Menaquinone-7 - Vitamin K2 Subtype - MedChemExpress

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Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs (orally active), is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. Menaquinone-7 has a well-researched potential in the prevention of aging-induced bone degeneration. Menaquinone-7 is also a pharmacological option for activating Gla matrix protein and intervening in the progression of calcific aortic stenosis (CAVS).

For research use only. We do not sell to patients.

Menaquinone-7 Chemical Structure

CAS No. : 2124-57-4

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Based on 3 publication(s) in Google Scholar

Other Forms of Menaquinone-7:

• Menaquinone-7-13C6 In-stock
• Menaquinone-7 (Standard) In-stock
• Menaquinone-7-d7 Get quote

Menaquinone-7 Related Antibodies

3 Publications Citing Use of MCE Menaquinone-7

• •Biomed Pharmacother. 2024 May 16:175:116697. [Abstract]
• •Int J Antimicrob Agents. 2025 Nov 25;67(1):107679. [Abstract]
• •J Sci Food Agric. 2025 Aug 30;105(11):5973-5985. [Abstract]

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• [1]. Yamaguchi M, et al. Inhibitory effect of menaquinone-7 (vitamin K2) on osteoclast-like cell formation and osteoclastic bone resorption in rat bone tissues in vitro. Mol Cell Biochem. 2001 Dec;228(1-2):39-47.

  [2]. Katsuyama H, et al. Menaquinone-7 regulates gene expression in osteoblastic MC3T3E1 cells. Int J Mol Med. 2007 Feb;19(2):279-84.

  [3]. Yamaguchi M, et al. Stimulatory effect of menaquinone-7 on bone formation in elderly female rat femoral tissues in vitro: prevention of bone deterioration with aging. Int J Mol Med. 2002 Dec;10(6):729-33.

  [4]. Peeters FECM, et al. Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using 18F-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design. Nutrients. 2018 Mar 21;10(4):386.

  [5]. Yamaguchi M, Taguchi H, Gao YH, Igarashi A, Tsukamoto Y. Effect of vitamin K2 (menaquinone-7) in fermented soybean (natto) on bone loss in ovariectomized rats. J Bone Miner Metab. 1999;17(1):23-9.

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Menaquinone-7 Related Classifications

• Disease Areas
• Blood or Cardiovascular Disease
• Cardiovascular Disease

• Cardiovascular Disease

• Do most proteins show cross-species activity?

  Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Menaquinone-72124-57-4Vitamin K2-7 Vitamin K2(35) Vitamin MK-7Menaquinone7Menaquinone 7Vitamin MK7Vitamin MK 7Vitamin MK-7OthersCAVSmarrow cellMC3T3E1 cellsosteoporosisanti-hemorrhagicInhibitorinhibitorinhibit

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