Molecular Basis Of Microbial One-Carbon Metabolism

Phishing Alert - GRC SPEAKERS AND DISCUSSION LEADERS ARE BEING TARGETED BY PHISHING ATTEMPTS DESIGNED TO COLLECT PAYMENT FOR REGISTRATION OR LODGING. CLICK HERE FOR MORE DETAILS

Molecular Basis of Microbial One-Carbon Metabolism

Gordon Research Conference Enzymes and Metabolisms Driving the Global Carbon Cycle August 7 - 12, 2022 Chair Vice Chair

Conference Description

Microorganisms metabolize and grow on a variety of one-carbon compounds including carbon dioxide, carbon monoxide, formate, methanol, methane, methylamines and methylthiols. The microbial metabolisms of one-carbon (C1) compounds are major metabolisms sustaining the global carbon cycle, which is important in marine and terrestrial environments. The microorganisms and their associated enzymes involved in the global carbon cycle attract both fundamental and applied interests due to the unique structure and function of key C1 metabolic enzymes and the fact that certain substrates, products, or intermediates of C1 metabolic pathways, such as carbon dioxide and methane, are potent green-house gasses. In addition, C1 metabolisms such as syngas fermentations are promising biological processes for biotechnological applications. The 2022 C1 Gordon Research Conference will highlight the most recent research on the aspects of microbial one-carbon metabolism and the enzymes involved in the global carbon cycle, including microbial CO2 fixation, photorespiration, chemolithoautotrophy, acetogenesis, methanogenesis, aerobic and anaerobic methane oxidation, microbial diversity, evolution in ecosystems and synthetic systems. Innovative applications of C1 metabolism in industrial processes will also be presented.

As in previous editions of this long-running meeting, the 2022 conference, with its associated GRS, will bring together early career and senior researchers and academics from the C1 research community. Investigators new to the field are encouraged to apply. The GRC format, with extensive discussions, interactive poster sessions, and informal gatherings in the afternoons and evenings, will provide an ideal setting for investigators from different fields and generations, to exchange ideas, brainstorm, and discuss opportunities for collaboration.

Related Meeting

This GRC will be held in conjunction with the "Molecular Basis of Microbial One-Carbon Metabolism" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm	Methane and the Carbon Cycle Discussion Leader:
7:40 pm - 7:50 pm	Introduction by Discussion Leader
7:50 pm - 8:15 pm	"A Nitrogenase-like Enzyme System Catalyzes Methionine, Ethylene, and Methane Biogenesis"
8:15 pm - 8:25 pm	Discussion
8:25 pm - 8:45 pm	"The Role of Rare-Earth Metals in Trace-Gas Metabolism by a Facultative Methanotroph"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:20 pm	"Post-translational Modification of Methyl-Coenzyme M Reductase in Methanogenic and Methanotrophic archaea"
9:20 pm - 9:30 pm	Discussion
Monday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Biochemistry and Physiology of Aerobic Methylotrophy Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:35 am	"Biochemistry of Copper-Dependent Methane Oxidation"
9:35 am - 9:45 am	Discussion
9:45 am - 10:10 am	"Atmospheric Methane Oxidizing Bacteria"
10:10 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:15 am	"Methanotroph: to Be, or Not to Be, that Is the Question"
11:15 am - 11:25 am	Discussion
11:25 am - 11:50 am	"The Industrial Yeast Pichia pastoris Is Converted from a Heterotroph into an Autotroph Capable of Growth on CO2"
11:50 am - 12:00 pm	Discussion
12:00 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Key Enzymes of Anaerobic C1 Metabolism Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 8:10 pm	"Catalytic Mechanism of Electron-Bifurcating Enzymes"
8:10 pm - 8:20 pm	Discussion
8:20 pm - 8:45 pm	"Activity-based Screens Developed to Target Novel Enzymes from Marine Resources"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:20 pm	"Molecular Basis of Carbon Fixation and Energy Conservation in Acetogens"
9:20 pm - 9:30 pm	Discussion
Tuesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	From C1 to C2: Acetogens, Reactions and Applications Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:35 am	"Electrons in the Fast Lane: Formate Production from Hydrogen and Carbon Dioxide in Acetogens"
9:35 am - 9:45 am	Discussion
9:45 am - 10:10 am	"Genome-Scale Analysis of Syngas Fermenting Acetogenic Bacteria"
10:10 am - 10:20 am	Discussion
10:20 am - 10:50 am	Group Photo / Coffee Break
10:50 am - 11:15 am	"Identification of the Elusive Ni-based Organometallic Intermediates in the Mechanism of Anaerobic CO and CO2 Fixation by the Wood-Ljungdahl Pathway"
11:15 am - 11:25 am	Discussion
11:25 am - 11:45 am	"One Carbon at a Time: Modeling Acetyl Coenzyme A Synthase Reactivity in an Engineered Metalloprotein"
11:45 am - 11:55 am	Discussion
11:55 am - 12:20 pm	"Stepping on the Gas Towards a Circular Economy: Commercial Scale Carbon Recycling via Gas Fermentation"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Ecology and Evolution of C1 Metabolism Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 8:05 pm	"Rates and Regulation of C1 Metabolism in the Gulf of Mexico"
8:05 pm - 8:15 pm	Discussion
8:15 pm - 8:40 pm	"The Habitability of Gas Hydrates in the Deep Subsurface and Microbial Adaptations to these Extreme Habitats"
8:40 pm - 8:50 pm	Discussion
8:50 pm - 9:20 pm	"Methylotrophy on Drugs - the Example of a Pharmaceutical Environmental Contaminant"
9:20 pm - 9:30 pm	Discussion
Wednesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	CO2 Fixation and Photorespiration Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:35 am	"Improving and Expanding the Performance of the Reductive Glycine Pathway for Synthetic C1-Assimilation"
9:35 am - 9:45 am	Discussion
9:45 am - 10:10 am	"Multiprotein Condensate Formation in Beta-Carboxysome Biogenesis"
10:10 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:15 am	"The Different Faces of RubisCO in Bloom-Forming Cyanobacteria"
11:15 am - 11:25 am	Discussion
11:25 am - 11:50 am	"Evolution of Specificity and Entrenchment at the Dawn of Form I RubisCOs"
11:50 am - 12:00 pm	Discussion
12:00 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:00 pm - 7:30 pm	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
7:30 pm - 9:30 pm	Chemoautotrophy and Electrons Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 8:10 pm	"Biochemical Basis of Atmospheric H2 Oxidation"
8:10 pm - 8:20 pm	Discussion
8:20 pm - 8:45 pm	"Structures of Methanogenic Fdh-Hdr-Fmd Complexes Give Insight into Direct Electron Transfer and Electron Bifurcation Processes"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:20 pm	"Seeing is Believing: Observation of Single Geobacter Cells Transferring Electrons via Cytochrome Nanowires Secreted by Pili"
9:20 pm - 9:30 pm	Discussion
Thursday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	C1 Metabolism and Physiology Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:35 am	"New Mode of Methanogenesis Observed in an Aromatic Compound Demethoxylating Archaeon"
9:35 am - 9:45 am	Discussion
9:45 am - 10:10 am	"Lanthanides in Methylotrophy"
10:10 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:15 am	"Variation of TCA cycle and Its Contribution of Carbon Fixation in (Hyper)thermophilic Archaea and Bacteria"
11:15 am - 11:25 am	Discussion
11:25 am - 11:50 am	"Biological Methane Formation Driven by Reactive Oxygen Species"
11:50 am - 12:00 pm	Discussion
12:00 pm - 12:20 pm	"Iminium Ion Hypothesis - How Different Reductases Share One Common Catalytic Mechanism"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	C1-Syntrophy Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 8:05 pm	"One-carbon Dinner for Two: Conversion of CO by Synthetic Microbial Co-cultures"
8:05 pm - 8:15 pm	Discussion
8:15 pm - 8:45 pm	"Syntrophy as an Essential Interaction in Methane Production"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:20 pm	"Abundance of Genes Encoding Carbon Monoxide Dehydrogenases in Early Volcanic Deposits"
9:20 pm - 9:30 pm	Discussion
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

Conference Links

Conference History Molecular Basis of Microbial One-Carbon Metabolism (GRS) Similar Conferences Registration Fees Additional Fee Info × Similar Gordon Research Conferences and Seminars

Enzymes, Coenzymes and Metabolic Pathways

July 26 - 31, 2026

Marine Microbes

June 7 - 12, 2026

Microbial One-Carbon Metabolism (GRS)

June 27 - 28, 2026 ×

Contact Us

MyGRC AccountCheck your application status, complete your registration, update your poster, change your rooming preference, make a bus reservation, print an invitation letter, print a receipt (which includes verification that you are presenting a poster) or print an invoice by logging into your account.

GRC VenuesEverything you need to know, to plan your trip.

FAQsInstant answers to common questions.

Tell us how we can help

Call us and leave a detailed message at: 401-783-4011

*This voicemail is only checked once daily. Due to high volume of requests during the conference season, responses may be delayed.

× You have no notifications ×

• Find a Conference
• Venues
  • North America
    • Bates College
    • Bryant University
    • Colby-Sawyer College
    • Four Points Sheraton
    • Grand Summit Hotel at Sunday River
    • Holderness School
    • Grand Galvez
    • Jordan Hotel at Sunday River
    • Mount Holyoke College
    • Proctor Academy
    • Salve Regina University
    • Sheraton Fairplex Hotel & Conference Center
    • Southern New Hampshire University
    • Stonehill College
    • University of Southern Maine
    • Ventura Beach Marriott
    • Waterville Valley
  • Asia
    • Hong Kong University of Science and Technology
    • Courtyard Marriott Hong Kong Sha Tin
  • Europe
    • Les Diablerets Conference Center
    • Renaissance Tuscany Il Ciocco
    • Rey Don Jaime Grand Hotel
• About GRC
  • Board of Trustees
  • Conference Evaluation Committee
  • President and CEO
  • Proposing a New Gordon Research Conference
  • GRC Connects
  • Funding Programs and Initiatives
  • Seed Funding for Gordon Research Seminars
  • History of GRC
  • Policies
• Support GRC

Contact Us

My GRC