Nguyen Thi Quy | Vietnam - Der Pharma Chemica

Der Pharma Chemica Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal. Nguyen Thi Quy Chemistry Faculty, Hanoi National University of Education, Hanoi, Vietnam

Publications

• Research Article Synthesis, Structural Characterization, Antimicrobial Activity of Complexes of Co(II), Ni(II), Cu(II), Zn(II), Cd(II) With 7-((2-Aminoethyl)Amino)-5-Bromo-6-Hydroxy-1-Methylquinolin-1- Ium-3-Sulfonate Author(s): Mai Phuong Chi, Nguyen Thi Quy and Le Thi Hong Hai* In this research, a new quinoline derivative, 7-((2-aminoethyl)amino)-5-bromo-6-hydroxy-1- methylquinolin-1-ium-3-sulfonate (QEt) as well as six complexes of Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II) with this ligand [M(QEt-1H)2].nH2O (M: Co, Cu, Zn, Cd, Hg), [Ni(QEt-1H)Cl].2H2O were synthesized. The molecular formulas and structures of the complexes were determined using measurement as IR, EDX, ESI-MS, 1H NMR spectra and thermal analysis. The bioactivity tests shown that the ligand and CuQEt complex have limiting effects to microorganisms, complexes CoQEt, ZnQEt, CdQEt and HgQEt exhibit antibacterial activities with low IC50 values, from 0.5 to 56.0 μg/mL and be most effective to Bacillus subtilis. Especially HgQEt inhibits effectively to almost types of bacteria... Read More»

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