Top 14+ Nu7441 Nhej hay nhất
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1.NU7441 | STEMCELL Technologies
107,00 US$ NU7441 is an inhibitor of DNA-dependent protein kinase (DNA-PK), an enzyme involved in the non-homologous end joining (NHEJ) DNA repair pathway.
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2.Inactivation Of DNA-PK By Knockdown DNA-PKcs Or ... - PubMed
The DNA-dependent protein kinase (DNA-PK) complex plays a pivotal role in non-homologous end-joining (NHEJ) repair. We investigated the mechanism of NU7441, ...
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3.DNA-PK Inhibition By NU7441 Enhances Chemosensitivity To ... - NCBI
9 thg 3, 2017 · A major pathway for the repair of DNA DSBs is non-homologous end-joining (NHEJ), which requires DNA-dependent protein kinase (DNA-PK) ... Abstract · MATERIALS AND METHODS · RESULTS · DISCUSSION
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4.NU7441 (KU-57788) - DNA-PK Inhibitor - Selleck Chemicals
Xếp hạng 5,0 (200) It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage. NU7441 (KU-57788) Chemical Structure. CAS No. 503468-95- ...
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5.KU-57788 (NU7441) | DNA-PK Inhibitor - MedChemExpress
Xếp hạng 5,0 (15) KU-57788 (NU7441) is a highly potent and selective DNA-PK inhibitor with an IC50 of 14 nM. KU-57788 is an NHEJ pathway inhibitor. KU-57788 also inhibits PI3K ...
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6.NU7441 (KU-57788) As NHEJ Inhibitors - J&K Scientific LLC
12 thg 5, 2022 · NU7441 (KU-57788) as NHEJ Inhibitors Biological Activity NU7441 selectively inhibits DNA-dependent protein kinase (DNA-PK), ...
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7.NU 7441 Supplier | CAS 503468-95-9 | KU 57788 - Tocris Bioscience
Xếp hạng 5,0 (1) 29 thg 2, 2020 · Also enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency 2 to 3-fold, and decreases nonhomologous end-joining (NHEJ) ...
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8.Nontoxic Concentration Of DNA‐PK Inhibitor NU7441 Radio ...
24 thg 6, 2016 · As recent studies suggested that high LET radiation mainly affects the nonhomologous end-joining (NHEJ) pathway of DNA double strand break ...
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9.STEMCELL Technologies NU7441 10 Mg Products - Fisher Scientific
Fisher Scientific - STEMCELL NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK) Shop STEMCELL Technologies NU7441 at Fishersci.se.
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10.Nu7441 | Sigma-Aldrich
Results 1 - 30 of 34 · DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a distinct factor in the non-homologous end-joining (NHEJ) pathway involved ...
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11.HDR Stimulation By NU7441 And KU-0060648 Is Comparable To ...
Suppression of Ku70 and Ku80 by siRNAs in the 293/TLR line followed by introduction of Cas9/sgRNAs decreased NHEJ approxi- mately 1.6-fold while stimulating HDR ...
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12.Effect Of NU7441 On The Activation Of Crucial DNA Damage Response...
The DNA-dependent protein kinase (DNA-PK) complex plays a pivotal role in non-homologous end-joining (NHEJ) repair. We investigated the mechanism of NU7441, a ...
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13.Inactivation Of DNA-PK By Knockdown ... - Spandidos Publications
16 thg 1, 2018 · We investigated the mechanism of NU7441, a highly selective DNA-PK inhibitor, in NHEJ-competent mouse embryonic fibroblast (MEF) cells and ...
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14.Fig. 5 - Retrovirology
From: NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase. Fig. 5. Effect of DNA-PKcs inhibitor Nu7441 on ...
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