PHYTOMENADIONE = VITAMIN K1 Injectable

Skip to main content MSF.org MSF Staff

• English
• العربية
• Español
• Français

.هذه الصفحة غير متاحة باللغة العربية Esta página no está disponible en este idioma. Cette page n’est pas disponible dans cette langue. This page is not available in this language.

All guidelines

Essential drugs

Essential drugs

English العربية Spanish French

Clinical guidelines - Diagnosis and treatment manual

English العربية Spanish French

Essential obstetric and newborn care

English العربية French

Management of A CHOLERA EPIDEMIC

English French

Management of A MEASLES EPIDEMIC

English French

Tuberculosis

English French

Public health engineering

English French

• Authors/Contributors
• Preface
• Foreword
• Use of the guide
• Abbreviations and acronyms
• Oral drugs
• Injectable drugs
  • ACETAMINOPHEN injectable
  • ADRENALINE injectable
  • ALBUTEROL injectable
  • AMOXICILLIN/CLAVULANIC ACID = CO-AMOXICLAV injectable
  • AMPHOTERICIN B conventional injectable
  • AMPHOTERICIN B liposomal injectable
  • AMPICILLIN injectable
  • ARTESUNATE injectable
  • ARTESUNATE (with arginine and sodium bicarbonate solvent) injectable
  • ATROPINE injectable
  • AZITHROMYCIN injectable
  • BENZATHINE BENZYLPENICILLIN injectable
  • BENZYLPENICILLIN = PENICILLIN G injectable
  • BENZYLPENICILLIN PROCAINE = PENICILLIN G PROCAINE injectable
  • BUTYLSCOPOLAMINE injectable
  • CALCIUM GLUCONATE injectable
  • CEFOTAXIME injectable
  • CEFTRIAXONE injectable
  • CHLORAMPHENICOL injectable
  • CLINDAMYCIN injectable
  • CLOXACILLIN injectable
  • CO-AMOXICLAV injectable
  • DEXAMETHASONE injectable
  • DIAZEPAM injectable
  • DICLOFENAC injectable
  • DIGOXIN injectable
  • EFLORNITHINE injectable
  • EPINEPHRINE = EPN = ADRENALINE injectable
  • ETONOGESTREL subdermal implant
  • FLUCONAZOLE injectable
  • FUROSEMIDE injectable
  • GENTAMICIN injectable
  • GLUCOSE 50% = DEXTROSE 50% injectable
  • HALOPERIDOL injectable
  • HALOPERIDOL decanoate injectable
  • HEPARIN sodium injectable
  • HYDRALAZINE injectable
  • HYDROCORTISONE injectable
  • HYOSCINE BUTYLBROMIDE = BUTYLSCOPOLAMINE injectable
  • INSULIN injectable
  • INSULIN, INTERMEDIATE-ACTING injectable
  • INSULIN, LONG-ACTING injectable
  • INSULIN, SHORT-ACTING injectable
  • INSULIN, BIPHASIC injectable
  • ISOSORBIDE DINITRATE injectable
  • KETAMINE injectable
  • LABETALOL injectable
  • LEVETIRACETAM = LEV injectable
  • LEVONORGESTREL subdermal implant
  • LIDOCAINE = LIGNOCAINE injectable
  • MAGNESIUM SULFATE = MgSO4 injectable
  • MEDROXYPROGESTERONE acetate injectable
  • MELARSOPROL injectable
  • METHYLERGOMETRINE injectable
  • METOCLOPRAMIDE injectable
  • METRONIDAZOLE injectable
  • MIDAZOLAM injectable
  • MORPHINE injectable
  • NALOXONE injectable
  • NOREPINEPHRINE tartrate = NEP = NORADRENALINE tartrate injectable
  • OMEPRAZOLE injectable
  • ONDANSETRON injectable
  • OXYTOCIN injectable
  • PARACETAMOL = ACETAMINOPHEN injectable
  • PENICILLIN G injectable
  • PENTAMIDINE injectable
  • PHENOBARBITAL = PB injectable
  • PHENYTOIN = PHT injectable
  • PHYTOMENADIONE = VITAMIN K1 injectable
  • POTASSIUM CHLORIDE 15% = KCl 15% injectable
  • PROMETHAZINE injectable
  • PROTAMINE injectable
  • SODIUM BICARBONATE 8.4% injectable
  • STREPTOMYCIN injectable
  • SURAMIN injectable
  • THIAMINE = VITAMIN B1 injectable
  • TRAMADOL injectable
  • TRANEXAMIC acid injectable
  • VALPROIC acid = VPA = SODIUM VALPROATE injectable
  • VITAMIN B1 injectable
  • VITAMIN K1 injectable
• Infusion fluids
• Vaccines, immunoglobulins and antisera
• Drugs for external use and antiseptics
• Drugs potentially dangerous or obsolete or ineffective
• Part two
• Main references

Breadcrumb

• Home
• Essential drugs
• Injectable drugs

PHYTOMENADIONE = VITAMIN K1 injectable Select language: English (Arabic) العربية Español (Spanish) Français (French) Enter Permalink Download Comment Return to top On this page

Last updated: March 2024

Prescription under medical supervision

Therapeutic action

• Vitamin, anti-haemorrhagic

Indications

• Prophylaxis and treatment of haemorrhagic disease of the newborn

Forms and strengths, route of administration

• 2 mg ampoule (10 mg/ml, 0.2 ml), for oral administration, IM or slow IV injection

Dosage

Prophylaxis of haemorrhagic disease of the newborn By IM route, the day of birth:

• Neonate < 1.5 kg: 0.5 mg single dose
• Neonate ≥ 1.5 kg: 1 mg single dose

Treatment of haemorrhagic disease of the newborn By IM or slow IV route: 1 mg every 8 hours if necessary, depending on clinical evolution and coagulation tests results

Contra-indications, adverse effects, precautions

• May cause: allergic reactions, especially by IV route; haematoma at IM injection site.
• Pregnancy: no contra-indication
• Breast-feeding: no contra-indication

Remarks

• Also comes in 10 mg ampoules (10 mg/ml, 1 ml) for use in adults only (treatment of haemorrhage due to antivitamin K agents, etc.) .
• Vitamin K1 is also used as prophylaxis for neonatal hypoprothrombinemia in mothers treated with enzyme-inducing antituberculosis drugs (rifampicin, rifabutin) during pregnancy. Use 10 mg ampoules (10 mg/ml, 1 ml): administer 10 mg/day of vitamin K1 by oral route for 15 days before birth. This maternal prevention does not change the need for IM administration of vitamin K1 in neonates.
• Do not dilute or mix with other drugs in the same syringe.

Storag

– Below 25 °C Path

Book traversal links for PHYTOMENADIONE = VITAMIN K1 injectable

• PHENYTOIN = PHT injectable
• POTASSIUM CHLORIDE 15% = KCl 15% injectable