Propargyl-O-C1-amido-PEG3-C2-NHS Ester | ADC Linkers ...

• •Nucleic Acid Gel Electrophoresis
• •Vector Construction
• •Restriction Endonuclease
• •Materials
• •PCR & qPCR
• •RT-PCR
• •Sequencing

• •Protein Sample Preparation
• •Protein Purification
• •Protein Electrophoresis & WB
• •Multiple Fluorescent Staining
• •Immunoassay
• •Immunoprecipitation Kit
• •Labeling Kit

• •Cell Culture
• •Cell Analysis
• •3D Cell Culture
• •Cell Isolation

• Cytokines and Growth Factors
• Immune Checkpoint Proteins
• CAR-T Related Proteins
• CD Antigens
• Fc Receptors
• Receptor Proteins
• Enzymes & Regulators
• Complement System
• Ubiquitin Related Proteins
• Viral Proteins
• Biotinylated Proteins
• Fluorescent-labeled Recombinant Proteins
• GMP-grade Proteins
• Animal-free Recombinant Proteins
• Others
• View More

• Interleukin & Receptors
• Interferon & Receptors
• Chemokine & Receptors
• TNF Superfamily
• CSF & Receptors
• TGF-beta Superfamily
• PDGFs & PDGFRs
• VEGF & VEGFR
• EGF Superfamily
• FGF Family
• HGF & Receptors
• Neurotrophic Factors
• Ephrin/Eph Family
• Angiopoietins
• IGF family
• Peptide Hormone & Neuropeptides

• Inhibitory Checkpoint Molecules
• Stimulatory Immune Checkpoint Molecules
• Butyrophilins

• CD4
• CD19
• CD27 Ligand/CD70
• CD123
• CD138/Syndecan-1
• Epithelial Cell Adhesion Molecule (EpCAM)
• Folate Receptor 1
• GPC-3
• Guanylate Cyclase 2C
• ErbB2/HER2
• ErbB3/HER3
• c-Met/HGFR
• MSLN
• CA-125
• ROR1
• CEACAM-5
• Prostate Specific Membrane Antigen
• TROP-2
• Siglec-6
• Folate Receptor alpha (FR-alpha)
• CD314/NKG2D
• CD319/SLAMF7
• Siglec-3/CD33
• CD7
• MUC-1/CD227

• T Cell CD Proteins
• B Cell CD Proteins
• NK Cell CD Proteins
• Macrophage CD Proteins
• Monocyte CD Proteins
• Stem Cell CD Proteins
• Platelet CD Proteins
• Erythrocyte CD Proteins
• Dendritic Cell CD Proteins
• Epithelial cell CD Proteins
• Endothelial cell CD Proteins
• Signal Transduction-related CD Proteins
• Cell Adhesion-related CD Proteins

• Fc-gamma Receptor
• FcRn
• Fc-epsilon Receptor
• Fc alpha/mu Receptor
• Polymeric Immunoglobulin Receptor
• FcμR
• Fc Receptor-like Proteins
• Immunoglobulin Fc Region
• Fc alpha RI/CD89

• Receptor Tyrosine Kinases
• Receptor Serine/Threonine Kinases
• Receptor Tyrosine Phosphatase
• Receptor Guanylyl Cyclase Family
• Cell Adhesion Molecules (CAMs)
• G-Protein-Coupled Receptors (GPCRs)
• Nuclear Receptor Superfamily
• Pattern Recognition Receptors
• Notch family
• Siglec
• Leukocyte Immunoglobin-like Receptors
• Killer-Cell Immunoglobulin-like Receptors
• Cytokine Receptors

• Oxidoreductases (EC 1)
• Transferases (EC 2)
• Hydrolases (EC 3)
• Lyases (EC 4)
• Isomerases (EC 5)
• Ligases (EC 6)
• Translocases (EC 7)
• Matrix Metalloproteinases
• ADAMs/ADAMTSs
• Cathepsin
• Carboxypeptidase
• Angiotensin-converting Enzymes
• Caspase
• Carbonic Anhydrase
• Serine/Threonine Kinase Proteins
• Protein Tyrosine Kinases
• Phosphatase
• Topoisomerase
• Protease Inhibitors
• Protein Kinase Inhibitor Peptide (PKI)
• Cyclin-Dependent Kinase Inhibitor Proteins
• Cystatin Family

• Complement Component 1
• Complement Component 2
• Complement Component 3
• Complement Component 4
• Complement Component 5
• Complement Component 6
• Complement Component 7
• Complement Component 8
• Mannose-binding Protein
• MASP-1
• MASP-2
• Complement Regulatory Proteins
• Complement Receptor
• Complement Component 9

• Ubiquitin/UBLs
• Ubiquitin Enzymes
• Deubiquitinase

• SARS-CoV-2 Proteins
• Zika Virus Proteins
• RSV Proteins
• Hepatitis C Virus Proteins
• Hepatitis B Virus Proteins
• HIV Proteins
• HPV Proteins
• Influenza Viruses Proteins
• Dengue Virus Proteins
• Ebola Virus Proteins
• Bacterial/Fungal Proteins
• CHIKV

• Molecular Biology
• •Nucleic Acid Gel Electrophoresis
• •Vector Construction
• •Restriction Endonuclease
• •Materials
• •PCR & qPCR
• •RT-PCR
• •Sequencing
• Protein Biology
• •Protein Sample Preparation
• •Protein Purification
• •Protein Electrophoresis & WB
• •Multiple Fluorescent Staining
• •Immunoassay
• •Immunoprecipitation Kit
• •Labeling Kit
• Cell Biology
• •Cell Culture
• •Cell Analysis
• •3D Cell Culture
• •Cell Isolation
• View More

• Nucleic Acid Gel Stain
• Agarose
• Loading & Running Buffer
• DNA Marker

• Seamless Cloning
• Ligase
• Endonuclease

• Polymerase Chain Reaction (PCR)
• Real-Time PCR
• DNA Polymerase

• Reverse transcription PCR
• RNase Inhibitor

• Enzymes

• Cell Lysis
• Washing Buffer
• Protease Inhibitor Cocktail
• Phosphatase Inhibitor Cocktail
• Deacetylase Inhibitor Cocktail
• Kinase Inhibitor Cocktail
• Protein Assay

• Magnetic Stand
• Magnetic Beads
• Affinity Chromatography Column
• Agarose Beads
• Equilibration Buffer
• Magnetic Agarose Beads

• Electrophoresis Buffer
• Protein Marker
• Transfer Buffer
• Blocking Buffer
• Binding/Washing Buffer
• Chemiluminescent Detection
• Loading Buffer
• Protein Staining Solution
• Gel Preparation Kit
• Antibody Dilution Buffer
• Protein Gel

• Cell Transfection
• Mycoplasma Clearance
• Sterile Antibiotic Solution
• Cell Freezing
• CEPT cocktail
• Basal Cell Culture Media
• Balanced Salt Solutions
• Cell Culture Supplements
• Dissociation Reagents
• Cell Separation Media
• Specialized Cell Culture Medium
• Lentivirus

• Cell Proliferation and Cytotoxicity
• Reporter Gene Testing
• Phalloidin Dye Conjugates
• Cell Apoptosis and Necrosis
• AntiFade Mounting Medium
• Mitochondrial Isolation
• Exosome Isolation, Purification and Detection
• Organelle Research
• Metabolism Assay Kit
• Mycoplasma Detection
• Biochemical Assay Kit
• Endotoxin Detection

• Basement Membrane Matrix
• Tumor Organoid Culture Medium
• Normal Tissue Organoid Culture Medium
• Organoid Research
• PSC Induction Product Series

• Topics
• Articles
• Product Guides
• Learning & Download
• Biomedical Dictionary
• Blogs
• Protocols

• Exhibition Events
• Promotion
• Free Sampling
• MCE Webinar

• Quality Management System
• Custom Synthesis Service
• Bulk and Custom Synthesis Service
• ADC-Related Custom Services
• PROTAC-Related Custom Services
• Custom Reference Standard Products
• Custom Peptide Synthesis
• Protein Expression Service
• Recombinant Antibody Expression Service
• Protein Crystal Structure Elucidation
• Oligonucleotide Synthesis
• Gene Regulation Tool
• • Lentivirus Packaging
• • Adenovirus Packaging
• • Adeno Associated Virus Packaging
• Fluorescent Labeling Service
• Custom Synthesis of Stable Isotope-Labeled Compounds
• One-stop CDMO Service
• One-stop Compound Screening Platform
• Virtual Screening
• Molecular Dynamics Simulation
• Cell-based Compound Screening
• Ion Channel Screening
• Kinase Screening Service
• SPR Assay Service
• GPCR Bioassay Screening Services
• Nuclear Receptor Screening Services
• Affinity Mass Spectrometry
• DEL Synthesis and Screening
• Molecular Interaction Assay Service
• Drug Target Identification Service
• AI Driven Drug Screening
• Molarity Calculator
• Dilution Calculator

• Careers

1. Antibody-drug Conjugate/ADC Related
2. ADC Linker
3. Propargyl-O-C1-amido-PEG3-C2-NHS ester

Solubility

In Vivo Dissolution Calculator

Help & FAQs

Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-O-C1-amido-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

Propargyl-O-C1-amido-PEG3-C2-NHS ester Chemical Structure

CAS No. : 2101206-78-2

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Propargyl-O-C1-amido-PEG3-C2-NHS ester Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All ADC Linker Isoform Specific Products:

• Biological Activity

• Purity & Documentation

• References

• Customer Review

• [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

• Rating
• Lot Number *
• Submit an Image No file chosen (Maximum size is: 1024 Kb)
• PubMed ID
• If you have published this work, please enter the PubMed ID.
• Show My Name
• Your name will appear on the site.
• Email
• Remarks

Propargyl-O-C1-amido-PEG3-C2-NHS ester Related Classifications

• Click Chemistry
• Alkynes ADC Synthesis

• Disease Areas
• Cancer

• Cancer
• Cancer Targeted Therapy Cancer Immunotherapy

• Antibody-drug Conjugate/ADC Related
• ADC Linker

• Molarity Calculator

• Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

• Do most proteins show cross-species activity?

  Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Propargyl-O-C1-amido-PEG3-C2-NHS ester2101206-78-2ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name	Requested Quantity *	mg g kg t ml l
Applicant Name *	Salutation	Dr. Prof. Mr. Ms. Mrs. Miss.
Email Address *	Phone Number *
Department	Organization Name *
City	State
Country or Region *	United StatesCanadaUnited KingdomAustraliaChinaGermanyFranceJapanKorea SouthSwitzerland------------------------------AlbaniaAlgeriaArgentinaArmeniaAustraliaAustriaAzerbaijanBahrainBangladeshBarbadosBelarusBelgiumBoliviaBosnia HerzegovinaBrazilBulgariaCameroonCanadaChileChinaColombiaCroatiaCyprusCzech RepublicDenmarkEcuadorEgyptEstoniaFijiFinlandFranceGeorgiaGermanyGibraltarGreeceHong Kong, ChinaHungaryIcelandIndiaIndonesiaIranIraqIrelandIsraelItalyJapanJordanKazakhstanKenyaKorea SouthKuwaitLatviaLebanonLibyaLithuaniaLuxembourgMacedoniaMalaysiaMaltaMexicoMoldovaMonacoMongoliaMontenegroMoroccoNepalNetherlandsNew ZealandNigeriaNorwayOmanPakistanParaguayPeruPhilippinesPolandPortugalPuerto RicoQatarRepublic of BeninRomaniaRussiaSaudi ArabiaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSri LankaSurinameSwedenSwitzerlandSyriaTaiwan, ChinaThailandTunisiaTurkeyUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVenezuelaVietnamZambiaZimbabweMacao, ChinaVaticanAndorraGhanaOther Countries
Please select a local distributor ナミキ商事株式会社 コスモ・バイオ株式会社 重松貿易株式会社
Remarks

Bulk Inquiry

Inquiry Information

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

• [email protected]
• 609-228-6898
• Find Your Local Distributor

Thanks, your subscription has been confirmed. You will hear from us soon.

Submission failed, please try again later.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy