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February Molecule of the Month

Histones Across the Tree of Life
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Latest Entries
As ofWed Feb 04 2026
9MZJ
CryoEM structure of GluK2 bound to glutamate in the deep desensitized state 2

9I3L
Structure of E.coli ribosome with filamin mutant Y719E nascent chain at linker length of 47 amino acids, with tRNA

9NFA
Cryo-EM structure of Ro60/La/minimal misfolded pre-5S rRNA complex with Fab, composite map

9I2E
NMT1-NAC bound human ribosome (combined translational states)

9CX0
Crystal structure of HLA-A*03:01 E152V mutant in complex with a mutant PIK3CA peptide

9I4C
Structure of anti-EV71 human monoclonal antibody 17-1-12A Fab

9CWY
Crystal structure of HLA-A*03:02 in complex with a wild-type PIK3CA peptide

9MZP
CryoEM structure of GluK2 bound to glutamate in the shallow desensitized state, composite map

9VE8
The MIDN Catch-IRF4 (A8L) fusion protein

9M53
Crystal structure of 1L-myo-inositol 1-phosphate synthase 1 from Oryza sativa
Features & Highlights

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Advanced Search Redesigned to Drive 3D Structure Discovery
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Announcement: Ligand Expo To Be Retired February 13, 2026
Users should transition to RCSB PDB and wwPDB services as soon as possible

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wwPDB Shared Responsibilities on Data Processing
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Learn to Use Mol* for 3D Visualization
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Milestone: >20,000 Structures Deposited to the PDB in 2025
wwPDB has received a record number of depositions this year
See new feature archiveNews
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February 4 is World Cancer Day
PDB structures reveal how cell growth is normally controlled, and how cancer cells circumvent these essential controls» 02/01/2026
Impact of PDB Structures on Anti-Cancer Drug Approvals
Open access to PDB data facilitates discovery and development of life saving drugs.» 01/27/2026
January is Cervical Cancer Awareness Month
Visit PDB-101 to learn how the capsid protein of papillomavirus is used in vaccines that prevent cervical cancer» 01/20/2026
Winter Newsletter Published
Highlights 2026 IUCr workshops; 2025 in review; and a new molecular animation showcasing Vitamin A and Vision. In the Education Corner, learn about BioStine: A Self-Training Platform in Structural Biology.» 01/15/2026
Top Molecules of the Month in 2025
Which articles were read the most in 2025?» 01/12/2026
PDB-101 Focus in 2026: Biotechnology
PDB-101 materials explore how researchers are using biology in industry» 01/06/2026
Molecular Explorations for 2026
Download our new calendar that highlights the work of Molecule of the Month creator Janet Iwasa» 12/28/2025
Happy Holidays
Season's greetings from RCSB PDB» 12/19/2025
PDB-101 Focus: Peak Performance
PDB-101 materials explore the structural biology of nutrition.» 12/15/2025
Structural Biology and Nobel Prizes
The Nobel Prize Award ceremony will take place on December 10. Visit PDB-101 to explore connections between Nobel Prizes and more than 50 years of open access to the PDB archive.» 12/07/2025
Molecule of the Month

Histones Across the Tree of Life
Uncovering the evolutionary diversity of histones
Read MoreQuarterly News (see archive)
Issue 108 - January 2026
This issue highlights upcoming IUCr workshops; 2025 deposition statistics, a new molecular animation highlighting Vitamin A and Vision and more.
Education Corner: Learn about BioStInE: a self-training platform in structural biology designed for students and researchers.
- Fall 2025 Issue
- Summer 2025 Issue
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Annual Reports

2024 Annual Report
Download the 2024 Annual Report (PDF) for an overview of recent activities and the global impact of PDB data and RCSB PDB services.
Annual Report Archive
PDB at a Glance 248,636 Experimental PDB Structures 382 Integrative PDB Structures 79,116 Structures of Human Sequences20,926 Nucleic Acid Containing Structures CSM at a Glance999,251 AlphaFoldDB69,326 ModelArchiveMore Statistics- About
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