Thalidomide-5-CH2-NH2 Hydrochloride | E3 Ligand Of PROTAC

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1. PROTAC Autophagy Apoptosis
2. E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis
3. Thalidomide-5-CH2-NH2 hydrochloride

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Thalidomide-5-CH2-NH2 (hydrochloride) is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-CH2-NH2 (hydrochloride) can be connected to the ligand for protein by a linker to form PROTACs.

For research use only. We do not sell to patients.

Thalidomide-5-CH2-NH2 hydrochloride Chemical Structure

CAS No. : 1010100-22-7

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Thalidomide-5-CH2-NH2 hydrochloride Related Antibodies

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• [1]. Makbul C, Nassal M, Böttcher B. Slowly folding surface extension in the prototypic avian hepatitis B virus capsid governs stability. Elife. 2020;9:e57277. Published 2020 Aug 14.

  [2]. Sato T, Ito T, Handa H. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.

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Thalidomide-5-CH2-NH2 hydrochloride Related Classifications

• Cancer
• Cancer Targeted Therapy Cancer Metabolism and Metastasis

• PROTAC Autophagy Apoptosis
• E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis

• Molarity Calculator

• Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

• Do most proteins show cross-species activity?

  Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thalidomide-5-CH2-NH21010100-22-7E3 Ligase Ligand-Linker ConjugatesAutophagyApoptosisInhibitorinhibitorinhibit

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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.