Thalidomide-NH-C5-NH2 | E3 Ligase Ligand-Linker Conjugates

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1. PROTAC Autophagy Apoptosis
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3. Thalidomide-NH-C5-NH2

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Help & FAQs

Thalidomide-NH-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Thalidomide-NH-C5-NH2 hydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Thalidomide-NH-C5-NH2 Chemical Structure

CAS No. : 2093386-39-9

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Other In-stock Forms of Thalidomide-NH-C5-NH2:

Other Forms of Thalidomide-NH-C5-NH2:

• Thalidomide-NH-C5-NH2 hydrochloride In-stock
• Thalidomide-NH-C5-NH2 TFA In-stock

Thalidomide-NH-C5-NH2 Related Antibodies

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• [1]. Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.

  [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

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Thalidomide-NH-C5-NH2 Related Classifications

• Disease Areas
• Cancer

• Cancer
• Cancer Targeted Therapy Cancer Metabolism and Metastasis

• PROTAC Autophagy Apoptosis
• E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis

• Molarity Calculator

• Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

• Do most proteins show cross-species activity?

  Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thalidomide-NH-C5-NH22093386-39-9E3 Ligase Ligand-Linker ConjugatesAutophagyApoptosisInhibitorinhibitorinhibit

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